Lab Bioreagents Buffers have been developed through the screening of >2000 compounds with the support of machine learning (AI) and optimized through kinetic and dynamic binding tests.
StrongBlock (I, II, III) are newly developed blocking buffers that provides exceptional performance and broad compatibility for Western blot, ELISA, IHC and nucleic acid detection assays. The blocking buffer is to block excess binding sites on the micro-plate for reducing non-specific binding signal, by which the assay sensitivity and specificity are improved. As many factors can influence nonspecific binding, there is no single blocking buffer that is ideal for each assay. For example, depending on the recognition of detection probes from different assays, one individual blocking buffer may cross-react with detection probe. StrongBlock (I, II, III) are a variety of buffers designed by different blocker components. During the assay, the test different blocking buffers helps to develop an immunoassay with low background noise and high signal-to-noise.
StrongBlock (I) is based on physically pre-treated and chemically modified casein. StrongBlock II is based on physically pre-treated BSA. StrongBlock III is based on physically pre-treated and chemically modified casein blocker and a series of heterogenous blockers.