Early symptoms of pertussis are similar to a common cold, however, later stages can be life threatening. Vaccinated individuals may still get sick, but with milder symptoms.1 The MGB Alert Bordetella P/PP primer mix ASR § amplifies, while the probe mix ASR detects, nucleic acids within the IS481 and IS1001 repeat regions of Bordetella pertussis and B. parapertussis. Melt curve analysis discriminates the two species.
1 Centers for Disease Control and Prevention. (2022, August 4). Pertussis (Whooping Cough) Signs and Symptoms. Centers for Disease Control and Prevention. Retrieved November 17, 2022, from https://www.cdc.gov/pertussis/about/signs-symptoms.html
§Analyte Specific Reagent. Analytical and performance characteristics are not established.