GenScript's new DNA Encoded Chemical Library (GenDECL) kit will revolutionize your pharmaceutical hit discovery and chemical biology research. In partnership with a leading technology expert, GenScript has developed this ready-to-use, commercially accessible GenDECL kit. This kit is a promising tool for fueling drug discovery efforts, consisting of a collection of 18 libraries with over 400 million chemical molecules that are encoded with amplifiable, unique DNA barcodes. The molecule constructs are developed to mimic molecule structures that have been identified in the drug development industry.
A merge between DNA-encoding and combinatorial chemistry, the GenDECL kit is suitable for large-scale screening. Offering convenience, affordability, and reliability, scientists can skip complex chemical library development, synthesis and analysis by leveraging the GenDECL kit. The GenDECL screening against the target protein can be conducted in a single test tube, using common laboratory equipment.
Description
The GenDECL kit consists of a libraryof diverse drug-like chemical compounds. Each compound is linked to a unique DNA barcode tag thatenables identification of the molecules that may bind with your protein of interest. The library interacts with thetarget protein, after which the bound compounds are eluted and amplified. Sequencing of the unique barcodesenables identification of compounds that interact with the target protein.GenScript’s DNA-Encoded Chemical Library (GenDECL) kit simplifies large-scalelibrary screening to identify binding properties of your protein of interest.GenDECL’s library contains a variety of diverse drug-like molecules, each linked toa DNA barcode for easy identification of compounds that bind with the targetprotein. Offering convenience, affordability, and reliability, scientists can skipcomplex chemical library development, synthesis and analysis by utilizing theGenDECL kit.
Key Features:
Accessible and Affordable: The GenDECL kit is a reliable, accessible and affordable kit.
Diverse Compound Library: Chemical Library consists of a collection of 18 libraries - over 400 million diverse molecules.
Analysis Included: Conducted by industry expert and included as part of the GenDECL solution.