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GeminiBio

GMP Human IL-2 (c126s)

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Recombinant Human Interleukin-2 (IL-2 C126S), also known as T cell growth factor (TCGF), is essential in promoting adaptive cellular immunity and tolerance, primarily via its direct effects on T cells. The major source of IL-2 is from activated CD4+ or activated CD8+ T cells. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages. In addition, IL-2 stimulates regulatory T cell development indicating a critical role in the prevention of autoimmunity. Taken together, IL-2 is an indispensable growth factor for immune system homeostasis.

Manufactured with the highest quality standards and rigorous quality control procedures ensure lot-to-lot consistency providing reproducibility in downstream cell culture processes.

Source: Genetically modified E. coli.

AA Sequence: MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFSQSII STLT

Product Reconstitution: Sterile 10 mM HCl at 0.1 mg/mL

For cell culture, further manufacturing, or research use only. Not for direct therapeutic use.

Lyophilized. Ships 2-8°C. Store frozen at -20°C

  • Purity: ≥ 97% determined by reducing and non-reducing SDS-PAGE analysis
  • Endotoxin: < 0.01 EU/µg using USP <85> / EP 2.6.14
  • Bioactivity: ED50 is determined by the dose-dependent Proliferation of CTLL- 2 cells. The ED50 is typically less than 3 ng/mL. The international units of CTGrade rh IL-2C126S is approximately 1.8 x 104 IU/µg, which is calibrated against recombinant Human Interleukin 2 WHO International Standard (NIBSC code 86/500).

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Thomas No.
CHM03Z622
Mfr. No.
300-950P-100
Description
Human IL-2 (c126s), GMP, 100 µg
list price/quantitytotal
$0.00
Thomas No.
CHM03Z623
Mfr. No.
300-950P-1MG
Description
Human IL-2 (c126s), GMP, 1 mg
list price/quantitytotal
$0.00
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