SIGMA Periodic acid, for electrophoresis, =99%

Formula: H₅IO₆

Formula Weight: 227.94

CAS No.: 10450-60-9

Purity: ≥99%

Application: Periodic acid is commonly used as a component for glycoprotein stains¹. Selective staining of glycoproteins on SDS-PAGE and membranes is carried out using a modification of the Periodic Acid-Schiff (PAS) method. Staining of sugar moieties of glycoproteins yields magenta bands with a colorless background. The Periodic Acid/Schiff Reagent stains vicinal diol groups found mainly on peripheral sugars and sialic acids and is used as a general glycoprotein stain². Periodic acid is also used to cleave reversible cross-linkers (e.g. DATD, DHEBA) in PAGE gels.

Analysis Note: Tested for use in staining of glycoproteins.