Synonym(s): α,α,α-Trifluoro-p-tolylboronic acid; 4-(Trifluoromethyl)benzeneboronic acid; [p-(Trifluoromethyl)phenyl]boronic acid
Formula: CF3C6H4B(OH)2
Formula Weight: 189.93
CAS No.: 128796-39-4
Purity: ≥95.0%
Application: Reagent used for
• Site-selective Suzuki-Miyaura cross-coupling reactions
• Palladium-catalyzed direct arylation reactions
• Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence
• Ruthenium catalyzed direct arylation
• Ligand-free copper-catalyzed coupling reactions
• Amination and conjugate addition reactions
• Regioselective arylation and alkynylation by Suzuki-Miyaura and Sonogashira cross-coupling reactions
• Rhodium-catalyzed asymmetric 1,4-addition reactions
• Copper-catalyzed nitration reactions
• Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation
Reagent used in Preparation of
• Thiazole derivatives for printable electronics
• Terphenyl benzimidazoles as tubulin polymerization inhibitors
Other Notes: Contains varying amounts of anhydride
Packaging: 1, 5 g in glass bottle
Beilstein Registry Number: 3544189
Melting Point: 245-250°C(lit.)
Empirical Formula (Hill Notation): C5H5ClN2