Cell inserts are commonly used in cell experiments, such as: co-culture experiments, chemotaxis experiments, cell migration experiments, cell invasion and drug transport experiments. Permeable supports may effectively improve the culture of polar cells, since these supports allow cells to secrete on and absorb molecules from their basal and apical surfaces to metabolize in a more natural way, as well as to stimulate the in vivo environment to the maximum extent for culturing of some special cell lines.
Polycarbonate (PC)
The membrane has excellent cell adhesion and therefore is suitable for transport studies and other applications that need to achieve optimal cell growth. Besides, PC membrane is also very for barrier analysis. Compare to other membrane materials, PC membrane has higher, more persistent and more stable trans-epthelial electrical resistance (TEER) values. PC membrane can be used to culture most types of cells without matrix coating.
PET membrane
With better optical clarity, it facilitates cell observation under a microscope and cell imaging.