Mitomycin C is the most widely used of the Mitomycin antibiotics because it is the least toxic and with the most potent antitumor activity.
- Inhibitor of DNA synthesis, nuclear division, and cancer cells.
- Antibacterial to gram positive, gram negative, acid-fast bacilli.
- Mitomycin C decomposes DNA in cancer cells by forming a complex with DNA and inhibits division of cancer cells by interfering with the biosynthesis of DNA.
Grade: Antibiotic Class
Potency: 850 µg/mg minimum
Key Applications: Antibacterial agent
Product Type: Biochemicals
Chemical Class: Pharmaceuticals
Extinction Coefficient (E1%): EmM(367 nm) = 21.84 (water); EmM(357 nm) = 22.78 (methanol); E1%(216 nm) = 742 (methanol); E1%(360 nm) = 742 (methanol); E1%(560 nm) = 0.06 (methanol)(Lit.)
Presentation: Blue Powder
Format: Powder
Formulation: Contains 2 mg/vial of pure mitomycin C.
pH: pH stability is at a pH of 6 to 9 pKa: 3.2, 6.5(Lit.)
Solubility: Soluble in dilute aqueous acids or dilute aqueous bases.
Storage & Handling: Store at +4°C.