Amoxicillin is a bactericidal penicillin active against both Gram-positive and Gram-negative organisms and is sensitive to β-Lactamase. Like benzylpenicillin, it is bactericidal against sensitive organisms during the stage of active multiplication. Amoxicillin exerts its mode of action by interfering with bacterial cell wall synthesis by acylating the enzyme transpeptidase, thus rendering it unable to cross-link muramic acid containing peptidoglycan strands. This inhibition of the biosynthesis of dipeptidoglycan, a substance necessary for cell wall strength and rigidity, results in a defective cell wall.
Cell culture tested. May cause sensitization by inhalation and skin contact.
Warning: For laboratory use only. Not fit for household, clinical use or human consumption.
Appearance: Solid
Boiling Point : 743.2 °C
IUPAC_Name: (2S,5R,6R)-6-[[(2R)-2-Azanyl-2-Phenyl-Ethanoyl]Amino]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid Trihydrate
Melting Point: >200°C (lit.)(dec.)