Antigen: human ARC amino acids 191-208
Host: rabbit
Cross Reactivity: (+) human and mouse ARC
Application(s): IP and WB
ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3.