Antigen: human Akt1 containing phospho-serine473
Host: mouse, clone 104A282
Isotype: IgG2κ
Cross Reactivity: (+) human and mouse Akt1
Application(s): IP and WB
Akt/PKB is a serine/threonine kinase that mediates cell survival and is thought to be a critical factor in the genesis of cancer. The major phosphorylation sites required for activation are Thr308 and Ser473.