Chemical structure: glycopeptide
Molecular Formula: C66H75Cl2N9O24 · HCl
Molecular Weight: 1485.71
Linear Structural Formula: C66H75Cl2N9O24 · HCl
Storage: 2-8C
Application: Vancomycin, from Streptomyces orientalis, is used for the treatment of serious or severe infections caused by susceptible strains of methicillin-resistant (ß-lactam-resistant) staphylococci. It is used to block bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis. It is widely studied in cancer patients. Vancomycin's overuse has been studied, which has resulted in recommended guidelines.
Biochem Physiol Actions: Vancomycin is a glycopeptide antibiotic that blocks bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis. It inhibits incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. It is effective against Gram-positive bacteria. Vancomycin also alters bacterial-cell-membrane permeability and RNA synthesis.
Other Notes: Keep container tightly closed in a dry and well-ventilated place.
Safety Statements (Europe): 36/37
Signal Word: Warning
Hazard statements: H317
Precautionary statements: P280