Squalene

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Squalene
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  • Squalene

    MP Biomedicals

    …of squalene to mice has resulted in marked increases in cellular and non-specific immune functions in a dose-dependent manner. Squalene may also act as a "sink" for highly lipophilic xenobiotics. Since it is a nonpolar substance, it has a higher affinity for un-ionized drugs. Squalene

  • Squalene

    Spectrum Chemical

    CAS No.: 111-02-4

  • SIGMA Squalene >=98%, liquid

    MilliporeSigma

    Synonym(s): 2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene Empirical Formula: C30H50 Linear Formula: [(CH3)2C[=CHCH2CH2C(CH3)]2=CHCH2-]2 Formula Weight: 410.72 MDL…

  • Squalene, 98%

    BeanTown Chemical

    CAS: 111-02-4 EC No: 203-826-1 MDL No: MFCD00008912 Liquid Molecular Formula: C30H50 MW: 410.73 Melting Point: -75° Boiling Point: 285°/22 mmHg Flash Point: 110°C (230°F) Density (g/mL): 0.858 Refractive Index: 1.494

  • Squalene, 98%

    Alfa Aesar

    Synonym(s): 2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene Formula: C30H50 Formula weight: 410.73 Purity: 98% CAS Number: 111-02-4 Harmonized Tariff Code:  2901.29

  • SUPELCO Squalene, analytical standard

    MilliporeSigma

    Synonyms: 2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene Formula: [(CH3)2C[=CHCH2CH2C(CH3)]2=CHCH2-]2 Formula Weight: 410.72 CAS No.: 111-02-4 Density: 0.858 g/mL at 25 °C(lit.)

  • human SQLE-6*his fusion protein

    Proteintech

    The human SQLE-6*his fusion protein from Proteintech is 143 - 508 aa of human SQLE expressed in E. coli with the expression vector T-HIS. This protein has been detected in SDS-page gel. The protein is lyophilized powder.

  • SIGMA 2,3-Oxidosqualene >=92.0% (HPLC)

    MilliporeSigma

    Synonym(s): 2,3-Epoxy-2,3-dihydrosqualene; 22,23-Epoxy-2,6,10,15,19,23-hexamethyl-2,6,10,14,18-tetracosapentaene; Squalene 2,3-epoxide; Squalene 2,3-oxide MDL Number: MFCD00871184 Purity: ≥92.0% (HPLC) Storage: −20°C

  • Corilagin

    Cayman Chemical

    A polyphenol and hydrolyzable tannin that inhibits squalene epoxidase (IC50 = 4.0 µM), a key enzyme in cholesterol synthesis; has various anti-inflammatory and anti-cancer effects.

  • (±)-Alliin

    Cayman Chemical

    A cysteine sulfoxide constituent of garlic that exhibits anti-cancer, anti-microbial, anti-hypertensive, cardioprotective, and anti-oxidant activities; inhibits squalene monooxygenase (IC50 = 120 μM), a rate-limiting step in the downstream pathway of cholesterol biosynthesis.

  • YM-53601

    Cayman Chemical

    Inhibits squalene synthase activity in rat hepatic microsomes and human Hep-G2 cells (IC50 values of 90 and 79 nM, respectively); inhibits cholesterol biosynthesis in rats reducing both cholesterol and triglyceride levels in plasma.

  • Terbinafine (hydrochloride)

    Cayman Chemical

    An antifungal compound clinically used to treat nail and skin infections; inhibits ergosterol synthesis at the stage of squalene epoxidation (IC50 = 30 nM for C. albicans); induces cell cycle arrest at the G0/G1 stage in COLO 205 tumor cells and human vascular endothelial cells.

  • Zaragozic Acid A

    Cayman Chemical

    A reversible competitive inhibitor of squalene synthase (Ki = 78 pM in vitro); reduces cholesterol synthesis in HepG2 cells (IC50 = 6 µM) and inhibits hepatic cholesterol synthesis in mice (ED50 = 0.2 mg/kg); also inhibits FPTase and GGPTase-I (IC50s = 216 and…

  • Monoclonal Anti-SEC14L2 antibody produced in mouse, clone 2E5, purified…

    MilliporeSigma

    …lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different…

  • SUPELCO Aliphatic Hydrocarbons Kit

    MilliporeSigma

    ….1 g; Nonane 1 g; Octacosane 1 g; Octadecane 1 g; 1-Octadecene .5 g; Octane 1 g; 1-Octene .5 g; Pentacosane .1 g; Pentane 1 g; Squalane 1 g; Squalene 1 g; Tetracontane .1 g; Tetracosane 1 g; Tetradecane 1 g; 1-Tetradecene .5 g; Tetratetracontane .1 g; Tetratriacontane .1 g; Triacontane .1 g;…

  • Bacitracin zinc salt, from Bacillus licheniformis, meets USP testing…

    MilliporeSigma

    … Formula Weight: 1486.07 CAS No.: 1405-89-6 Storage Temperature: 2-8°C Application: Bacitracin is used to study the disruption of bacterial cell wall synthesis at the level of peptidoglycan biosynthesis and isoprenyl metabolism. Used to study the biosynthesis of sterols and squalene.

  • Monoclonal Anti-FDFT1 antibody produced in mouse, clone 3C2, purified…

    MilliporeSigma

    …specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. (provided by RefSeq) Immunogen: FDFT1 (AAH03573, 1 a.a. ~ 417 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26…

  • ALDRICH trans,trans-Farnesol, 96%

    MilliporeSigma

    … 222.37 CAS No.: 106-28-5 Purity: 96% Density: 0.879g/mLat 25°C(lit.) Application: Employed in the synthesis of terpenes, such as squalenes, cembranoids, and forskolin. 3, Other Notes: A sesquiterpene alcohol found in many essential oils. Packaging: 10 g in poly bottle

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