Methotrexate

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Methotrexate
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  • Methotrexate solution 1ML

    MilliporeSigma

  • SIGMA Methotrexate hydrate, powder, BioReagent, suitable for cell culture,…

    MilliporeSigma

    Synonym(s): 4-Amino-10-methylfolic acid hydrate; L-4-Amino-N 10 -methylpteroylglutamic acid hydrate; L-Amethopterin hydrate; Antifolan hydrate; MTX hydrate; Methylaminopterin hydrate Formula: C20H22N8O5 · xH2O Formula Weight: 454.44…

  • Methotrexate

    Amresco

    Grade: USP Molecular Weight: 454.44

  • Aminopterin

    LKT Labs

    Aminopterin is a folic acid analog and derivative of pterin; it is very similar to methotrexate in structure. Aminopterin exhibits anticancer chemotherapeutic and immunosuppressive activities. Like other folic acid analogs, aminopterin inhibits dihydrofolate reductase, depleting nucleotide pools and…

  • Methotrexate disodium salt, 98.5%

    Alfa Aesar

    Formula: C20H20N8Na2O5 Formula weight: 498.40 Purity: 98.5% CAS Number: 7413-34-5 UN Number: UN2811 Hazard Class: 6.1 Packing Group: III Harmonized Tariff Code:  2933.59 Hazard Statements: H301 Toxic if swallowed. Precautionary Statements: …

  • Methotrexate, 100MG, UN2811

    MilliporeSigma

  • Methotrexate

    MilliporeSigma

    pharmaceutical secondary standard; traceable to USP and PhEur Synonym(s): Methotrexate; (+)-Amethopterin; 4-Amino-10-methylfolic acid; 4-Amino-N 10 -methylpteroyl-L-glutamic acid; Antifolan; MTX; Methylaminopterin Empirical Formula: C20H22N8O5

  • Methotrexate

    BeanTown Chemical

    CAS: 59-05-2 EC No: 200-413-8 MDL No: MFCD00150847 RTECS: MA1225000 UN No: UN1544; Haz Class: 6.1; Packing Group: III Powder Molecular Formula: C20H22N8O5 MW: 454.44 Melting Point: 185-204°

  • Methotrexate

    MP Biomedicals

    …similar to folic acid. Methotrexate is a mixture of 4-amino-10-methylfolic acid and closely related compounds. A potent anticancer agent. Blocks DNA synthesis by blocking the production of tetrahydrofolate cofactors required for the synthesis of thymidine. Methotrexate is actively transported…

  • Methotrexate

    MilliporeSigma

    European Pharmacopoeia (EP) Reference Standard Synonym(s): (+)-Amethopterin; 4-Amino-10-methylfolic acid; 4-Amino-N 10 -methylpteroyl-L-glutamic acid; Antifolan; MTX; Methylaminopterin Empirical Formula: C20H22N8O5 Formula Weight: 454.44 Linear…

  • Methotrexate

    Alfa Aesar

    Formula: C20H24N8O6 Formula weight: 472.45 CAS Number: 59-05-2 UN Number: UN1544 Hazard Class: 6.1 Packing Group: III Harmonized Tariff Code:  2933.59 Hazard Statements: H301-H360-H315-H319 Toxic if swallowed. May damage fertility or the unborn child. Causes skin irritation.…

  • Methotrexate

    Cayman Chemical

    An analog of folic acid and aminopterin that is used in the treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions; induces adenosine release, inhibits the metabolism of folic acid, and blocks key enzymes in the synthesis of purines and pyrimidines…

  • Methotrexate for peak identification

    MilliporeSigma

    European Pharmacopoeia (EP) Reference Standard Synonym(s): Methotrexate; (+)-Amethopterin; 4-Amino-10-methylfolic acid; 4-Amino-N 10 -methylpteroyl-L-glutamic acid; Antifolan; MTX; Methylaminopterin Empirical Formula: C20H22N8O5 Formula Weight: …

  • Methotrexate for system suitability

    MilliporeSigma

    European Pharmacopoeia (EP) Reference Standard Synonym(s): Methotrexate; (+)-Amethopterin; 4-Amino-10-methylfolic acid; 4-Amino-N 10 -methylpteroyl-L-glutamic acid; Antifolan; MTX; Methylaminopterin Empirical Formula: C20H22N8O5 Formula Weight: …

  • Methotrexate impurity E

    MilliporeSigma

    European Pharmacopoeia (EP) Reference Standard Synonym(s): 4-{[(2,4-Diaminopteridin-6-yl)methyl]methylamino}benzoic acid Empirical Formula: C15H14N7O2 Formula Weight: 324.32 Linear Formula: …

  • Methotrexate impurity D

    MilliporeSigma

    European Pharmacopoeia (EP) Reference Standard Synonym(s): 4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]methylamino}benzoic acid Empirical Formula: C15H12N6O3 Formula Weight: 324.29 Linear Formula: …

  • Methotrexate impurity C

    MilliporeSigma

    European Pharmacopoeia (EP) Reference Standard Synonym(s): Methopterine Empirical Formula: C20H21N7O6 Formula Weight: 455.42 Linear Formula: C20H21N7O6

  • Methotrexate hydrate, >=99.0% (sum of enantiomers, HPLC)

    MilliporeSigma

    CAS No.: 133073-73-1 Synonyms: 4-Amino-10-methylfolic acid hydrate; L-4-Amino-N 10 -methylpteroylglutamic acid hydrate; L-Amethopterin hydrate; Antifolan hydrate; MTX hydrate; Methylaminopterin hydrate Formula: C20H22N8O5 ¬? xH2O …

  • METHOTREXATE 500MG UN 1544PSN1 6.1 / PGIII

    MilliporeSigma

  • SIGMA Methotrexate hydrate >=98% (HPLC), powder

    MilliporeSigma

    Synonym(s): 4-Amino-10-methylfolic acid hydrate; L-4-Amino-N 10 -methylpteroylglutamic acid hydrate; L-Amethopterin hydrate; Antifolan hydrate; MTX hydrate; Methylaminopterin hydrate Empirical Formula: C20H22N8O5 -+ xH2O Linear Formula: …

  • SIGMA Methotrexate PharmaGrade, Manufactured under appropriate controls for use…

    MilliporeSigma

    Synonym(s): Methotrexate; (+)-Amethopterin; 4-Amino-10-methylfolic acid; 4-Amino-N 10 -methylpteroyl-L-glutamic acid; Antifolan; MTX; Methylaminopterin Empirical Formula: C20H22N8O5 Linear Formula: …

  • "Methotrexate-(methyl-13C,d3)"

    MilliporeSigma

    analytical standard Synonym(s): [ 13 C, 2 H3]-Methotrexate Empirical Formula: 13 CC19D3H19N8O5 Formula Weight: 458.45 Linear Formula: 13 CC19D3H19N8O5 MDL Number:…

  • Methotrexate-D3 solution 1ML

    MilliporeSigma

  • SIGMA Methotrexate-Agarose saline suspension

    MilliporeSigma

    MDL Number: MFCD00164466 Storage: 2-8°C

  • Methotrexate, meets USP testing specifications

    MilliporeSigma

    …Biochem/physiol Actions: Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the…

  • Calcium Folinate Pentahydrate

    LKT Labs

    Calcium folinate is commonly co-administered with methotrexate or other similar chemotherapeutics to provide a folate source for some dividing cells, such as bone marrow cells. Calcium folinate may inhibit thymidylate synthase. Grade: ≥95%

  • "Folinic acid calcium salt hydrate, "

    MilliporeSigma

    …and blocking the conversion of folic acid to tetrahydrofolate. In medicine, calcium folinate is used after treatment with methotrexate to reduce the toxicity of the methotrexate. Calcium folinate is also used to enhance the cytotoxic effect of 5-fluorouracil in the treatment of cancer. Packaging: …

  • L-Methionine sulfoximine

    MilliporeSigma

    …banks for production of recombinant proteins for therapeutics has resulted in two major systems for selection of stable and active clones, Methotrexate selection of dihydrofolate reductase (DHFR) overexpressing cells and MSX selection of glutamine synthetase overexpressing cells. Cells are grown…

  • Poly-D-Lysine Hydrobromide

    MP Biomedicals

    …the cells are not disrupted by excessive uptake of L-lysine. Other uses for poly-lysine have been reported as well: Conjugation to methotrexate for increased drug transport. Microencapsulation of islets. Use in simple reproducible procedure for chromosomal preparations from a variety…

  • Poly-L-Lysine Hydrobromide

    MP Biomedicals

    …increases the number of positively charged sites available for cell binding. Other applications of Poly-L-lysine include Conjugation to methotrexate for increased drug transport, Microencapsulation of islets, Use in simple reproducible procedure for chromosomal preparations from a variety…

  • Poly-L-Lysine Hydrobromide

    MP Biomedicals

    …for cells; however, certain cells can digest poly-lysine. Other uses for poly-lysine have been reported as follows: Conjugation to methotrexate for increased drug transport Microencapsulation of islets Use in simple reproducible procedure for chromosomal preparations from a variety…

  • Poly-L-Lysine, MW >=70,000

    MP Biomedicals

    …the attachment factor. Poly-L-Lysine is typically used as a coating substrate for culture dishes, slides, etc. It can be used in conjugation to methotrexate for increased drug transport. For Microencapsulation of islets. It is also use in simple reproducible procedure for chromosomal preparations…

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