Hepatochem

The Copper catalyzed amination kits  is the ideal tools for the investigation of Ullmann reaction conditions. This enables to conveniently screen multiple reaction conditions simultaneously using pre-weighed catalysts and reagents. We offer pre-selected arrays of precatalysts and salts or…

2 sets of photmethylation reaction conditions with 2 iridium catalysts,  AcOOtBu and 4 different solvent systems  16 reaction vials total.

The sulfinate alkylation reaction described by Prof. Baran is a powerful late stage functionalization tool. Our kit allows to conveniently produce analogues of the lead compound using 6 different sulfinate alkylation reagents. Each vial contains 100 μmol of sulfinate alkylation reagent and a…

Kit with PdOAc₂ with either AgF, SelectFluor, NFSI or TMPyF with or without PhIOPiv as oxidant 24 reaction vials totals.

Benefits : Facilitates screen of reaction conditions No glove-box needed to manipulate air sensitive or moisture sensitive reagents Enables up to 32 reaction conditions simultaneously Save substrate using low scale reaction conditions Save time on optimization Features: …

Lead diversification is becoming an viable alternative to de novo synthesis as C-H functionalization chemistry offers many possible transformations including hydroxylation, acetoxylation, methoxylation, and halogenation among others.  However each desired transformation can quickly become a…

… Fast nexpensive Rapid optimization Reproducible Scaleable to mg Convenient room temperature reagents Easy to use HepatoChem has developed a revolutionary way to screen, optimize, and produce metabolites directly from drug candidates. The BMO Kit exploits an optimized…

Thomas No. C802K88 2 sets of reaction conditions with iridium catalyst Ir(dF-CF3-ppy)2(dtbbpy)PF6, Ni/dtbbpy and 8 bases Cs2CO3, K3PO4, K2HPO4, KOH, Li2CO3,K2CO3, DABCO and DBU. 16 reaction vials total. Thomas No. C802K89 2 sets of reaction conditions with iridium catalyst…

This kit allows to identify reaction condition that produces glucuronide adduct of a drug compound. The reaction conditions are derivative of the Koenigs–Knorr reaction. This is a 2 step process: 1)  Coupling with glucuronidation reagent 2)  De-protection with NaOH/MeOH…

The amide coupling kits are ideal tools for the optimization of amide bond formation. This enables you to conveniently screen multiple reaction conditions simultaneously using pre-weighed reagents. We offer pre-selected arrays of reagents and salts or custom arrays depending on your needs. …

Experimental Details: In duplicate in a 4-ml vial equipped with a teflon septa and 2x7 mm stir bar, were weighed 4-bromoacetophenone (4.95 mg, 25 μmol) and potassium benzyltrifluoroborate (4.50 mg, 25 μmol, 1 equiv.). To this vial was added a 1.0 ml solution in DMA containing NiCl2-dme (1.1…

The EvoluChem™ PhotoRedOx Box device is designed to facilitate photochemical experiment. This device is compatible with most vial formats (0.3 ml, 2 ml, 4 ml and 20 ml vials). Its compact design allows for use with any stirring plate. A built-in fan keeps the reaction conditions at room…

Thomas No. 1160V24 This kit contains 1 reaction block (24x 2ml vial, 32X 0.3ml vial, 4X 2Dram vial), 1 decapper for 8 mm crimped vial and 1 syringe Hamilton 81000. Thomas No. 1160V25 1 reaction block (24x 2ml vial, 32x 0.3ml vial, 4x 2Dram vial) Thomas No. 1160V26 1…

The Pd Catalyzed Amination Kits  are ideal tools for the investigation of cross-coupling reaction conditions. This enables to conveniently screen multiple reaction conditions simultaneously using pre-weighed catalysts and reagents. The kit contains all reagents and supplies to perform the…