Cpla

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Cpla
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  • cPLA2 Assay Kit

    Cayman Chemical

    Arachidonoyl thio-PC is a substrate for cPLA2 by virtue of the presence of arachidonic acid at the sn-2 position of the glycerophospholipid. Hydrolysis of the arachidonoyl thioester bond at the sn-2 position by PLA2 releases free thiol which can be detected by DTNB. This assay can be used to…

  • Immunotag™ Mouse cPLA2 (Phospholipase A2, Cytosolic) ELISA Kit

    G-Biosciences

    An ELISA kit for the detection of cPLA2 (Mouse). This uses Sandwich ELISA, Double Antibody and has a sensitivity of 0.094ng/ml.

  • Immunotag™ Rat Cpla2 (Cytosolic Phospholipase A2) ELISA Kit

    G-Biosciences

    An ELISA kit for the detection of Cpla2 (Rat). This uses Sandwich ELISA, Double Antibody and has a sensitivity of 0.094ng/ml.

  • Phospholipase A2, Group Ivb (Cytosolic)

    Proteintech

    The PLA2G4B antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human PLA2G4B. This antibody recognizes human antigen. The PLA2G4B antibody has been validated for the following applications: ELISA, IHC, WB analysis.

  • Phospholipase A2, Group Ivf

    Proteintech

    The PLA2G4F antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PLA2G4F. This antibody recognizes human antigen. The PLA2G4F antibody has been validated for the following applications: ELISA, IHC analysis.

  • human PLA2G4C-6*his fusion protein

    Proteintech

    The human PLA2G4C-6*his fusion protein from Proteintech is 190 - 541 aa of human PLA2G4C expressed in E. coli with the expression vector PET28a. This protein has been detected in SDS-page gel. The protein is lyophilized powder.

  • human PLA2G4F-6*his fusion protein

    Proteintech

    The human PLA2G4F-6*his fusion protein from Proteintech is 111 - 330 aa of human PLA2G4F expressed in E. coli with the expression vector PET28a. This protein has been detected in SDS-page gel. The protein is lyophilized powder.

  • SIGMA Anti-TIP60 antibody produced in rabbit ~1 mg/mL, affinity isolated…

    MilliporeSigma

    Synonym(s): 60 kDa Tat interactive protein; HIV-1 Tat interactive protein; HTATIP; cPLA(2)-interacting protein; histone acetyltransferase HTATIP MDL Number: MFCD02686660 Storage: −20°C

  • iPLA2 (Type VI) Polyclonal Antibody

    Cayman Chemical

    Antigen: hamster iPLA2 amino acids 557-576 (PRFNQNINLKPPTQPADQLV) Host: rabbit Cross Reactivity: (+) human, mouse, bovine, hamster, and rat iPLA2; (−) cPLA2 and sPLA2 Application: WB

  • CAY10590

    Cayman Chemical

    A potent and selective inhibitor of sPLA2 that exhibits 95% inhibition (XI(50)=0.003) of sPLA2 without affecting the activities of cPLA2 or iPLA2.

  • SIGMA Anti-TIP60 antibody produced in rabbit ~1 mg/mL, affinity isolated…

    MilliporeSigma

    Synonym(s): 60 kDa Tat interactive protein; HIV-1 Tat interactive protein; HTATIP; cPLA(2)-interacting protein; histone acetyltransferase HTATIP MDL Number: MFCD02686660 Storage: −20°C

  • SIGMA Anti-TIP60 antibody produced in rabbit ~1 mg/mL, affinity isolated…

    MilliporeSigma

    Synonym(s): 60 kDa Tat interactive protein; HIV-1 Tat interactive protein; HTATIP; cPLA(2)-interacting protein; histone acetyltransferase HTATIP MDL Number: MFCD02686660 Storage: −20°C

  • CAY10650

    Cayman Chemical

    A highly potent (IC50 = 12 nM) cPLA2α inhibitor; demonstrates strong anti-inflammatory effects when applied topically at a dose of 0.1 mg/ear in a mouse model of acute irritant contact dermatitis.

  • AX 048

    Cayman Chemical

    A potent group IVA cPLA2 inhibitor (XI(50) = 0.022); reduces thermal hyperalgesia evoked by carrageenan injection of rat hind paw (ED50 = 1.2 mg/kg); does not inhibit COX activity or interfere with CB1 receptor signaling.

  • Pyrrophenone

    Cayman Chemical

    Reversible, selective inhibitor of cPLA2 with an IC50 value of 4.2 nM in enzyme assays; potently blocks the release of AA and the production of PGE2 and LTC4 in cells (IC50 = 24, 25, and 14 nM, respectively).

  • FKGK 11

    Cayman Chemical

    A selective inhibitor of iPLA2 that demonstrates an XI(50) value of 0.0073; in comparison, mole fractions as high as 0.091 do not inhibit cPLA2 activity and cause only slight inhibition of sPLA2.

  • sPLA2 (human Type V) Monoclonal Antibody (Clone MCL-3G1)

    Cayman Chemical

    Antigen: purified human recombinant sPLA2 (type V), W79A mutant Host: mouse Cross-Reactivity: (+) human sPLA2 (type V); (−) human sPLA2 (type IIa) and cPLA2 Application(s): ELISA, IHC (formalin-fixed paraffin-embedded tissue), and WB Isotype: IgG1 Clone designation: MCL-3G1

  • 10-Pyrene-PC

    Cayman Chemical

    10-Pyrene-PC is a substrate for all PLA2s with the exception of cPLA2 and PAF-AH. Upon phospholipid hydrolysis, 10-pyrenyldecanoic acid is produced from 10-pyrene-PC. The monomeric 10-pyrenyldecanoic acid exhibits fluorescence (excitation 345 nm, emission 395 nm), allowing quantitation of…

  • sPLA2 (mouse Type V) Polyclonal Antibody

    Cayman Chemical

    Immunogen: synthetic peptide from an internal region of mouse protein Host: rabbit Cross Reactivity: (+) human, mouse, and rat sPLA2 (mouse type V); (−) bee venom and human synovial sPLA2, iPLA2, and cPLA2 Species Reactivity: (+) Human, mouse, and rat sPLA2 Application(s): WB

  • Methyl Arachidonyl Fluorophosphonate

    Cayman Chemical

    A selective, active-site directed, irreversible inhibitor of cPLA2 and iPLA2; inhibits A23187-induced arachidonic acid release from human platelets (IC50 = 0.6 µM) and iPLA2 release from P388D1 cells (IC50 = 0.5 µM); a potent inhibitor of FAAH (IC50 = 2.5…

  • 1,2-bis(heptanoylthio) Glycerophosphocholine

    Cayman Chemical

    Diheptanoyl Thio-PC is a substrate for all PLA2s with the exception of cPLA2 and PAF-AH. Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB…

  • Arachidonoyl Serotonin

    Cayman Chemical

    An inhibitor of FAAH attenuating the FAAH activity from mouse neuroblastoma cells with an IC50 value of 12 µM; alters both the Km and the Vmax of FAAH, indicating that it is a very tight binding, competitive inhibitor; does not inhibit cPLA2 and is essentially devoid of…

  • CAY10502

    Cayman Chemical

    CAY10502 is a potent inhibitor of cPLA2α with an IC50 value of 4.3 nM for the purified enzyme from human platelets. It inhibits arachidonic acid mobilization from A23187-stimulated or TPA-stimulated human platelets with IC50 values of 570 and 0.9 nM, respectively.

  • Arachidonyl Trifluoromethyl Ketone

    Cayman Chemical

    ATK is an analog of arachidonic acid in which the carboxyl group is replaced by a trifluoromethyl ketone group. It inhibits the activity of the 85 kDa cPLA2 and the 80 kDa macrophage iPLA2 without altering the activity of the 14 kDa sPLA2s. ATK is useful for differentiating the effects of cPLA2 and…

  • Palmityl Trifluoromethyl Ketone

    Cayman Chemical

    PTK is an analog of palmitic acid in which the COOH group is replaced by trifluoromethyl ketone. In P388D1 cells, PTK inhibits iPLA2 activity with an IC50 value of 3.8 µM. A related compound, ATK is a less potent inhibitor of iPLA2 with an IC50 value of 15 µM. PTK…

  • Anti-PLA2G4D antibody produced in mouse, purified immunoglobulin, buffered…

    MilliporeSigma

    Synonyms: cPLA2delta Storage: -20C UNSPSC Code: 12352203 Features and Benefits: Antibody BioguaranteeEvaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. General…

  • Asiaticoside

    MP Biomedicals

    Antibacterial. Human collagen I synthesis inducer. Anti-wrinkle activity. Shows wound healing activity. Enhances normal human skin cell migration, attachment and growth. Suppresses collagen expression and TGF-beta/Smad signaling by inducing Smad7 and inhibiting TGF-betaRI and TGF-betaRII.…

  • Anti-PLA2G4D antibody produced in rabbit, purified immunoglobulin, buffered…

    MilliporeSigma

    Synonyms: cPLA2delta Storage: -20C UNSPSC Code: 12352203 Features and Benefits: Antibody BioguaranteeEvaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. General…

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