PG-010 is composed of a cyclic peptide that binds to the thrombopoietin receptor (TPOR) and functions as a growth factor substitute peptide, demonstrating agonistic activity towards TPOR.
Recombinant TPO and PG-010 activities were compared using ERK phosphorylation and JAK2-STAT5 reporter gene activation. The results indicated that PG-010 demonstrated activity nearly equivalent to TPO on a molar basis, showing similar activity to TPO at lower concentrations based on mass concentration (ng/mL).
- 10 µg of PG-010 exhibits equivalent activity to 26 µg of recombinant human TPO
- 25 µg of PG-010 exhibits equivalent activity to 65 µg of recombinant human TPO
Provided as lyophilized powder
Purity: greater than or equal to 95% (HPLC)
MW (Da): 7,148.02 (acetate)
https://peptigrowth.com/en/products/pg-010/
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