The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid…

CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86…

Specificity: Reacts with the heavy and light chains of turkey IgY Source: Pooled antisera from goats hyperimmunized with IgY Cross Adsorption: None; may react with immunoglobulins from other species and the light chains of other turkey immunoglobulins Purification: Affinity…

Specificity: Reacts with the heavy and light chains of human IgG and the light chains of human IgM and IgA Source: Pooled antisera from goats hyperimmunized with human IgG Cross Adsorption: Mouse, bovine, and horse serum proteins (SP); may react with immunoglobulins from other species …

Specificity: Reacts with the heavy and light chains of mouse IgG1, IgG2a, IgG2b, IgG2c, IgG3, IgM, and IgA Source: Pepsin digest of Goat Anti-Mouse Ig, Human ads (SB Cat. No. 1010) Cross Adsorption: Human immunoglobulins and pooled sera; may react with immunoglobulins from other species …

Specificity: Reacts with the heavy chain of C57BL/6 mouse IgG2c Source: Pooled antisera from goats hyperimmunized with mouse IgG2c Cross Adsorption: Mouse IgG1, IgG2a, IgG2b, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species …

Specificity: Reacts with the Fc region of human IgG Source: Pooled antisera from goats hyperimmunized with human IgG Cross Adsorption: Human IgG Fab, IgM, and IgA; may react with IgG from other species Purification: Affinity chromatography on human IgG Fc covalently linked to agarose …

Specificity: Reacts with mouse ? light chains Source: Pooled antisera from goats hyperimmunized with mouse ? light chains Cross Adsorption: Mouse ? light chains; may react with ? light chains from other species Purification: Affinity chromatography on mouse ? light chains covalently…

Specificity: Reacts with the heavy chain of human IgG Source: Pepsin digest of Goat Anti-Human IgG (SB Cat. No. 2040) Cross Adsorption: Human IgM and IgA; may react with IgG from other species Purification: Isotype: Goat F(ab')2 IgG Format/Conjugate: FITC (Fluorescein) Buffer…

CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and…

CD18 represents the common ß2 integrin subunit that associates non-covalently with the a/ß chains of CD11a, CD11b, and CD11c to form various integrin heterodimers. It is expressed strongly on lymphocytes and monocytes and weakly on granulocytes. CD18 mediates a variety of heterotypic and homotypic…

Specificity: Reacts with the heavy and light chains of mouse IgG and the light chains of mouse IgM and IgA Source: Pepsin digest of Rabbit Anti-Mouse IgG(H+L) (SB Cat. No. 6175) Cross Adsorption: Pooled human sera and immunoglobulins; may react with immunoglobulins from other species …

The CD23 antigen is the low affinity IgE Fc receptor, which is a 45-49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells) and can also be found on the surface of T cells, macrophages and platelets. It is distinct from…

Specificity: Reacts with the heavy and light chains of chicken IgY Source: Pooled antisera from goats hyperimmunized with IgY Cross Adsorption: None; may react with immunoglobulins from other species and the light chains of other chicken immunoglobulins Purification: Affinity…

Specificity: Reacts with the heavy chain of mouse IgG1 Source: Pooled antisera from goats hyperimmunized with mouse IgG1 Cross Adsorption: Mouse IgG2a, IgG2b, IgG3, IgM, and IgA; may react with immunoglobulins from other species Purification: Affinity chromatography on mouse IgG1…

CD45 is the common leukocyte antigen and is expressed on all cells of hematopoietic origin except erythrocytes. CD45 exists as a number of different isoforms which result from alternative RNA splicing of exons 4, 5 and 6. The I3/2.3 monoclonal antibody recognizes a framework epitope present on all…

CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage),…

Specificity: Reacts with the heavy chain of mouse IgG1 Source: Pooled antisera from goats hyperimmunized with mouse IgG1 Cross Adsorption: Mouse IgG2a, IgG2b, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …

CD90 (Thy-1), a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes, and neurons of all mouse strains. The…

Specificity: Reacts with the heavy and light chains of human IgG and the light chains of human IgM and IgA Source: Pooled antisera from rabbits hyperimmunized with human IgG Cross Adsorption: None; may react with immunoglobulins from other species Purification: Affinity chromatography on…

Specificity: Reacts with the heavy and light chains of human IgG and the light chains of human IgM and IgA Source: Pooled antisera from goats hyperimmunized with human IgG Cross Adsorption: Mouse, bovine, and horse serum proteins (SP); may react with immunoglobulins from other species …

Specificity: Reacts with the heavy chain of mouse IgG2b Source: Pooled antisera from goats hyperimmunized with mouse IgG2b Cross Adsorption: Mouse IgG1, IgG2a, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …

Specificity: Reacts with the heavy and light chains of chicken IgY Source: Pooled antisera from goats hyperimmunized with IgY Cross Adsorption: None; may react with immunoglobulins from other species and the light chains of other chicken immunoglobulins Purification: Affinity…

CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19…

Specificity: Reacts with the heavy chain of mouse IgG2a Source: Pooled antisera from goats hyperimmunized with mouse IgG2a Cross Adsorption: Mouse IgG1, IgG2b, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …

Specificity: Reacts with the heavy chain of mouse IgG1 Source: Pepsin digest of Goat Anti-Mouse IgG1, Human ads (SB Cat. No. 1070) Cross Adsorption: Mouse IgG2a, IgG2b, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species …

Murine CD72.1 (Lyb-2.1), a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 which is distributed on all T cells and…

Specificity: Reacts with the heavy and light chains of mouse IgG1, IgG2a, IgG2b, IgG2c, and IgG3 and with the light chains of mouse IgM and IgA Source: Pooled antisera from goats hyperimmunized with mouse IgG Cross Adsorption: None; may react with immunoglobulins from other species …

Specificity: Reacts with the heavy and light chains of rabbit IgM and IgG Source: Pooled antisera from goats hyperimmunized with rabbit IgG Cross Adsorption: Human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: Affinity chromatography …

Specificity: Reacts with the heavy chain of mouse IgG2a Source: Pooled antisera from goats hyperimmunized with mouse IgG2a Cross Adsorption: Mouse IgG1, IgG2b, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …

Specificity: Reacts with the heavy chain of mouse IgA Source: Pooled antisera from goats hyperimmunized with mouse IgA Cross Adsorption: Mouse IgG and IgM; may react with immunoglobulins from other species Purification: Affinity chromatography on mouse IgA covalently linked to agarose …

Specificity: Reacts with the Fc region of goat IgG Source: Pooled antisera from rabbits hyperimmunized with goat IgG Fc Cross Adsorption: Goat IgG Fab; may react with immunoglobulins from other species Purification: Affinity chromatography on goat IgG covalently linked to agarose …