β-estradiol is a potent mammalian estrogenic hormone produced by the ovary. Triggers the production of gonadotropins leading to ovulation. β-Estradiol is used to study cell differentiation and transformations (tumorigenicity). The pharmacology and HPLC determination of β-Estradiol…

Synonyms: 1,2,3-Tricaprinoylglycerol, 1,2,3-Tridecanoylglycerol, Glycerol tricaprate, Glycerol tris(decanoate), Tridecanoin, Glyceryl tridecanoate, 1,2,3-Tridecanoyl-rac-glycerol, Glyceryl tridecanoate, Tri-N-Caprin Molecular Formula: C₃₃H₆₂O₆

Safranine O is a biological stain used in histology, cytology, bacteriology. It is a redox and adsorption indicator.

β-NAD is one of the biologically active forms of nicotinic acid. Coenzyme of the dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols Inhibitory neurotransmitter in visceral smooth muscle Acts as a hydrogen acceptor, forming NADH …

D-Biotin is a growth factor present in small amounts in every living cell. It is involved in naturally occurring carboxylation reactions. It occurs mainly bound to proteins or polypeptides. It is more abundant in the liver, kidney, pancreas, yeast and milk. Biotin levels are higher in cancerous…

o-Nitrophenyl-β-D-galactoside (ONPG) is a colorimetric substrate for b-galactosidase. This product is hydrolyzed to o-nitrophenol by the enzyme. o-Nitrophenol is yellow in alkaline solution and can be quantitated at 410-420 nm 2 . o-Nitrophenyl-β-D-galactoside is a cell culture…

Collagenases degrade native helical collagen fibrils. Plays an important role in connective tissue metabolism Produced by specific cells involved in repairs and remodeling processes Type II enzyme that contains greater clostripain activity Collagenase is used for collagen…

Histamine Diphosphate Monohydrate is potent vasodilater. Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2₂ activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.

Indomethacin, an anti-inflammatory agent, inhibits Cox-1 and Cox-2 (cyclooxygenases) with selectivity for Cox-1 (IC50 of 230 nM) over Cox-2 (IC50 of 630 nM). Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor…

β-Mercaptoethylamine is a useful antioxidant .It is experimentally used as a radioprotective agent and It is also used to produce acute and chronic duodenal ulcers in rats and as an antidote to acetaminophen. β-Mercaptoethylamine derived from cysteine degradation is the simplest stable…

Folic acid, also known as folate, is a B vitamin that can be found in a variety of fruits and vegetables. Can be chemically synthesized Water soluble Exhibits metal binding properties Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs…

Folic acid, also known as folate, is a B vitamin that can be found in a variety of fruits and vegetables. It can also be chemically synthesized. Folate, a watersoluble vitamin, helps the body form red blood cells and aids in the formation of genetic material within every body cell. Folic Acid is a…

2-Hydroxypropyl-beta-Cyclodextrin are non-toxic solubilizers. The solubility of drugs increases linearly with the concentration of 2-Hydroxypropyl-b-cyclodextrin in aqueous buffer. The formation of drug/cyclodextrin complexes is a rapidly reversible reaction and complexes exist both in solution and…

Calcein is used as an indicator for the determination of calcium by titration with EDTA. Suitable for fluorometric determination of calcium. Calcein does not fluoresce in strong alkaline solution, but an intense fluorescence appears in the presence of alkaline earths, especially calcium. The…

Vitamin K is a group of structurally similar, fat-soluble vitamins. Vitamin K1 is used as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X; anticoagulant factors protein C and S and as a cell signaling factor.

1,1-Dimethylbiguanide hydrochloride (metformin) is a strong base. It forms well defined salts and possessing excellent coordination capacity with transition metals, forming highly colored bidentate chelate complexes. Metformin (MET) exists in various forms: diprotonated (H2MET)2+ in strong acidic…

Vancomycin inhibits bacterial mucopeptide biosynthesis. Vancomycin is a glycopeptide antibiotic that blocks bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis. It inhibits incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. It is effective against…

Adenosine-5'-triphosphate (ATP) disodium salt, >99%. Crystalline.

Glucose 6-phosphate (also known as Robison ester) is glucose sugar phosphorylated on carbon 6. Very common in cells Start of two major pathways: Glycolysis and Pentose phosphate pathway Can be converted into glycogen or starch for storage D-Glucose 6-phosphate is the core…

p-nitrophenol is used as an indicator in 0.1% alcohol solutions. 4-Nitrophenol is used as a precursor to prepare phenetidine, acetophenetidne and pH indicator. Its carboxylate ester derivatives are involved as an active component for the construction of amide moieties in peptide synthesis. It is…

Ampicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as…

Albumins are a group of acidic proteins which occur in the body fluids and tissues of mammals and in some plant seeds. Serum and plasma albumin is carbohydrate free and comprises 55-62% of the protein present. However, only about 40% of the total albumin in the body is in the circulating plasma at…

Albumins are a group of simple proteins found in the body fluids and tissues of animals and in some plant seeds. Unlike globulins, albumins have low molecular weights, are soluble in water, are easily crystallized and contain an excess of acidic amino acids. Serum and plasma albumin is…

β-NADP is a coenzyme necessary for the alcoholic fermentation of glucose and the oxidative dehydrogenation of other substances. It occurs widely in living tissue, especially in the liver. Nicotinic acid can be converted to nicotinamide in the body and, in this form, is found as a component of…

Fibrinogen is a blood protein that is involved in clotting and is converted to fibrin by thrombin. Fibrinogen has an approximate molecular weight of 340 kDa. It consists of three non-identical pairs of disulfidebonded chains. The α-chain has an approximate molecular weight of 63.5 kDa, the…

Prepared using Cohn method IV. The material is non-reactive for HbsAg, Anti-HCV 3.0, Anti-HIV-1/2 and STS (RPR). This material is also negative for HIV-1 and HCV by PCR ALBUMIN, HUMAN is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research;…

Cefoperazone sodium salt is a broad spectrum third generation cephalosporin antibiotic that has similar antimicrobial activity to ceftazidime. It is active against Pseudomonoas aeruginosa and it has enhanced activity against Enterobacteriaceae and Bacteroides sp. in the presence of the…

D-(+)-Trehalose dihydrate is a natural alpha-linked non –reducing disaccharide formed by an α,α-1,1-glucoside bond between two α-glucose units which yields 2 moles of D-glucose upon acid hydrolysis. Has 90% of the calorific content of sucrose. Inhibits polyglutamine-mediated…

Tetracycline is a broad spectrum polyketide antibiotic with clinical uses in treating bacterial infections such as Rocky Mountain spotted fever, typush fever, tick fevers, Q fever, and Brill-Zinsser disease and to treat upper respiratory infections and acne. It has been used in studies of multidrug…

Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. Amikacin must be given by the…

Tetracyline inhibits gram-positive, gram-negative and mycoplasma. It is used in tetracycline controlled gene expression systems (gene switches) such as the tet-on and tet-off systems. It is also used to select tetracyline resistant colonies in cell culture.

Melatonin is a hormone of the pineal gland. Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell…