Antimycin A was initially produced by Streptomyces. Antimycin A binds cytochrome c reductase, inhibiting electron transport chain activity, oxidative phosphorylation, and ATP synthesis. Antimycin A is used in research models to study mitochondrial respiration and superoxide production. Grade: ≥98%

Actinomycin D is a polypeptide antibiotic produced from Streptomyces; it exhibits anticancer chemotherapeutic activity but does not display antibacterial benefit. Actinomycin D is clinically used to treat various cancers and is one component of the VAC chemotherapy regimen. Actinomycin D binds DNA,…

Alternariol is a mycotoxin initially produced by species of Alternaria. Alternariol produces a weak estrogenic response in vitro and increases production of estradiol and progesterone. Alternariol is also cytotoxic; in macrophages, it increases DNA base oxidations and strand breaks. Also in…