LKT Labs
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Amitriptyline Hydrochloride
LKT LabsAmitriptyline exhibits antidepressant, antipsychotic, analgesic, and antinociceptive activities; it acts as an antagonist at 5-HT2A/2C/6/7 receptors, M1-5 muscarinic acetylcholine receptors (mAChRs), H1/4 histamine receptors, a1-adrenergic receptors, and also on the serotonin transporter (SERT) and…
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Dihydroartemisinin
LKT LabsDihydroartemisinin is a sesquiterpene lactone that can be derived from Artemisia. Dihydroartemisinin exhibits anticancer, antiviral, anti-inflammatory, anti-asthma, and anti-parasitic activities. Artemisinins such as dihydroartemisinin are best known for their antimalarial activity.…
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AGDV
LKT LabsAGDV is a C-terminal peptide sequence found on fibrinogen that is known as a binding site for glycoprotein IIb/IIIa (integrin aIIbß3); this binding is required for platelet adhesion and aggregation.
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Cilostazol
LKT LabsCilostazol is a quinolone inhibitor of phosphodiesterase 3B (PDE 3B) that exhibits vasodilatory, antiplatelet, anti-inflammatory, anti-diabetic, antidepressant, anxiolytic, and pro-angiogenic activities. Cilostazol is clinically used to treat intermittent claudication associated with peripheral…
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Betamethasone
LKT LabsBetamethasone is a glucocorticoid receptor agonist that exhibits anti-inflammatory, immunosuppressive, and anti-ulcerative activities. Betamethasone is clinically used to treat skin irritations such as psoriasis and to accelerate preterm fetal lung development.
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Citrinin
LKT LabsCitrinin is a mycotoxin initially produced by Penicillum, Aspergillus, and Monascus. Citrinin exhibits cytotoxic, cardiotoxic, nephrotoxic, and pro-oxidative activities. In leydig cells, citrinin inhibits testosterone production and induces caspase-mediated apoptosis. In embryos, citrinin alters…
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Apramycin Sulfate
LKT LabsApramycin is an aminoglycoside antibiotic originally produced by Streptomyces. Apramycin is clinically used in veterinary medicine. This compound binds 16S rRNA of the bacterial 30S ribosomal subunit, causing conformational changes in CA and GA base pairs and inhibiting RNA translocation.
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ß-Cembrenediol
LKT LabsCembrenediols are diterpenes originally found in Anisomeles. These compounds exhibit antibacterial activity against Mycobacterium and antifungal activity against Colletotrichum. Grade: ≥98%
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Chromium Picolinate
LKT LabsChromium picolinate is clinically used to decrease fasting blood glucose and insulin levels. Chromium picolinate exhibits anti-hyperlipidemic, cardioprotective, and anti-diabetic activities. In high-fat diet-fed rats, chromium picolinate decreases plasma lipid levels and platelet aggregation. In…
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Celecoxib
LKT LabsCelecoxib is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-2; it exhibits anti-inflammatory, analgesic, anticancer, and anti-metastatic activities. Celecoxib is clinically used to treat arthritis, acute pain, and ankylosing spondylitis. In hepatoma cells, celecoxib decreases the…
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L-Carnitine Hydrochloride
LKT LabsL-Carnitine is an endogenous quaternary ammonium compound required for fatty acid transport; it is often given as a dietary supplement. The L-isomer is active, exhibiting anti-osteoporotic, antioxidative, and cardioprotective activities. In a clinical setting, L-carnitine administration increases…
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Brevetoxin 2
LKT LabsBrevetoxins are lipid-soluble polyether neurotoxins initially produced by the dinoflagellate Karenia brevis. Brevetoxins act as agonists, binding the neurotoxin site 5 on SCN4A/Nav1.4 and SCN5A/Nav1.5 voltage-gated Na+ channels in skeletal muscle and cardiac tissue, producing a channel opening…
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Bitertanol
LKT LabsBitertanol is an antifungal pesticide; it acts as a demethylation inhibitor, preventing sterol biosynthesis and disrupting membrane function. Bitertanol increases glutathione-S-transferase activity in the liver of rats, displaying potential antioxidative activity. Additionally, bitertanol alters…
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Ciprofloxacin is a second generation fluoroquinolone antibiotic that exhibits antibacterial activity against both gram negative and gram positive bacteria. Ciprofloxacin inhibits DNA gyrase and topoisomerase IV, preventing DNA replication.
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ABT-199
LKT LabsBH3 mimetic and Bcl-2 inhibitor. It induces apoptosis in chronic lymphocytic leukemia cells
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Azithromycin Dihydrate
LKT LabsAzithromycin is an azalide macrolide antibiotic derived from erythromycin. Azithromycin binds the bacterial 50S ribosomal subunit, inhibiting protein translation. Azithromycin displays antibacterial, anti-fibrotic, and anti-inflammatory activities. In epithelial cells, azithromycin inhibits the…
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L-Citrulline
LKT LabsL-Citrulline is a by product of NO formation from metabolism of L-arginine that exhibits tocolytic and antioxidative activities. L-Citrulline was originally found in watermelon. In isolated rat uteri, L-citrulline decreases uterine contractile force through stimulation of the NO-cGMP relaxant…
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1,4-Benzoquinone
LKT Labs1,4-Benzoquinone is a precursor used in the synthesis of hydroquinone and is also used as a hydrogen acceptor and oxidant. 1,4-Benzoquinone exhibits anti-inflammatory and antibiotic activities. 1,4-Benzoquinone inhibits 5-lipoxygenase and prevents leukotriene synthesis. Additionally, this compound…
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Acivicin
LKT LabsAcivicin is a fermentation product of Streptomyces; it is a glutamine analog. Acivicin inhibits ?-glutamyl transferase, CTP synthetase, GMP synthetase, and FGAM synthetase, preventing purine synthesis. Acivicin exhibits anticancer and antifungal activity, although its potential chemotherapeutic…
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Boc-FAAGRK-AMC
LKT LabsThis peptide is a protease substrate that is used to measure protease activity in vitro. Grade: ≥98%
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Abamectin
LKT LabsF0F1-ATPase and adenine nucleotide translocator inhibitor and GABA receptor antagonist. It prevents mitochondrial respiration and decreases sperm count and motility. Grade: ≥70%
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Astilbin
LKT LabsAstilbin is a flavonoid found in several plants, including species of Engelhardia and Smilax. Astilbin displays anticancer, antioxidative, anti-inflammatory, and immunosuppressive activities. In vitro, astilbin inhibits expression of IL-1ß, IL-6, IL-10, MCP-1, and TNF-a, as well as activity of…
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Aristolochic Acid A
LKT LabsAristolochic acid A is a carcinogenic compound found in Aristolochia and Radix that has commonly been used in traditional Chinese medicine. This compound inhibits phospholipase A2 (PLA2) and decreases GABA-induced release of arachidonic acid and phosphatidylcholine as well as exocytosis in vitro.
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Anethole Trithione
LKT LabsAnethole trithione is an oltipraz analog that is clinically used to treat xerostomia (dry mouth). Anethole trithione enhances salivary gland secretion.
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Calcitonin gene-related peptide (CGRP) is an endogenous neuropeptide that exhibits anti-inflammatory, anti-resorptive, anxiogenic, neuroprotective, and pro-angiogenic activities. In animal models of livery injury, CGRP displays protective benefit, decreasing pro-inflammatory cytokine levels. CGRP…
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L-Carnitine Tartrate
LKT LabsL-Carnitine is an endogenous quaternary ammonium compound required for fatty acid transport; it is often given as a dietary supplement. The L-isomer is active, exhibiting anti-osteoporotic, antioxidative, and cardioprotective activities. In a clinical setting, L-carnitine administration increases…
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Aflatoxin B1
LKT LabsAflatoxins are mycotoxins found in foods and livestock feeds that were initially produced by species of Aspergillus. Aflatoxin B1 is the most cytotoxic of all aflatoxins; it inhibits DNA synthesis and induces cell cycle arrest.
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Chondroitin Sulfate, cow
LKT LabsChondroitin sulfate (CS) is a polyanionic sulfated glycosaminoglycan that displays anti-arthritic, antioxidative, and anti-inflammatory activities. CS is an endogenous component of the extracellular matrix of connective tissues and is responsible for their resistance and elasticity. CS is often…
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Caffeic Acid
LKT LabsCaffeic acid is a hydroxycinnamic acid found in coffee, argan oil, Eucaplyptus, Salvinia, and Phellinus; it exhibits antioxidative, anti-diabetic, antibiotic, anti-inflammatory, anti-metastatic, and anticancer activities. Caffeic acid inhibits activity of a-amylase and a-glucosidase. This compound…
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ß-Casomorphin, human
LKT Labsß-Casomorphin is a peptide fragment of casein that exhibits antioxidative and anti-fibrotic activities. In vivo, ß-casomorphin improves high glucose-induced changes in oxidative enzyme secretion and activity. ß-Casomorphin also decreases urinary glucose and protein levels as well as serum creatine…
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Adenine
LKT LabsAdenine is a purine nucleotide base that is involved in the synthesis of RNA and DNA. Adenine also plays roles in cellular respiration as a component of ATP, NAD, and FAD. Grade: ≥98%