Experimental Details: In duplicate in a 4-ml vial equipped with a teflon septa and 2x7 mm stir bar, were weighed 4-bromoacetophenone (4.95 mg, 25 μmol) and potassium benzyltrifluoroborate (4.50 mg, 25 μmol, 1 equiv.). To this vial was added a 1.0 ml solution in DMA containing NiCl2-dme (1.1…

The EvoluChem™ PhotoRedOx Box device is designed to facilitate photochemical experiment. This device is compatible with most vial formats (0.3 ml, 2 ml, 4 ml and 20 ml vials). Its compact design allows for use with any stirring plate. A built-in fan keeps the reaction conditions at room…

2 sets of photmethylation reaction conditions with 2 iridium catalysts,  AcOOtBu and 4 different solvent systems  16 reaction vials total.

Thomas No. 1160V24 This kit contains 1 reaction block (24x 2ml vial, 32X 0.3ml vial, 4X 2Dram vial), 1 decapper for 8 mm crimped vial and 1 syringe Hamilton 81000. Thomas No. 1160V25 1 reaction block (24x 2ml vial, 32x 0.3ml vial, 4x 2Dram vial) Thomas No. 1160V26 1…

Our BMO kits enable, in three simple steps, synthesis of metabolites directly from the parent drug. Key Benefits: Fast nexpensive Rapid optimization Reproducible Scaleable to mg Convenient room temperature reagents Easy to use HepatoChem has developed a…

This kit allows to identify reaction condition that produces glucuronide adduct of a drug compound. The reaction conditions are derivative of the Koenigs–Knorr reaction. This is a 2 step process: 1)  Coupling with glucuronidation reagent 2)  De-protection with…

Thomas No. C802K88 2 sets of reaction conditions with iridium catalyst Ir(dF-CF3-ppy)2(dtbbpy)PF6, Ni/dtbbpy and 8 bases Cs2CO3, K3PO4, K2HPO4, KOH, Li2CO3,K2CO3, DABCO and DBU. 16 reaction vials total. Thomas No. C802K89 2 sets of reaction conditions with iridium catalyst…

The amide coupling kits are ideal tools for the optimization of amide bond formation. This enables you to conveniently screen multiple reaction conditions simultaneously using pre-weighed reagents. We offer pre-selected arrays of reagents and salts or custom arrays depending on your needs. …

Benefits : Facilitates screen of reaction conditions No glove-box needed to manipulate air sensitive or moisture sensitive reagents Enables up to 32 reaction conditions simultaneously Save substrate using low scale reaction conditions Save time on optimization Features:…

The Copper catalyzed amination kits  is the ideal tools for the investigation of Ullmann reaction conditions. This enables to conveniently screen multiple reaction conditions simultaneously using pre-weighed catalysts and reagents. We offer pre-selected arrays of precatalysts and salts or…

The sulfinate alkylation reaction described by Prof. Baran is a powerful late stage functionalization tool. Our kit allows to conveniently produce analogues of the lead compound using 6 different sulfinate alkylation reagents. Each vial contains 100 μmol of sulfinate alkylation reagent and a…

Lead diversification is becoming an viable alternative to de novo synthesis as C-H functionalization chemistry offers many possible transformations including hydroxylation, acetoxylation, methoxylation, and halogenation among others.  However each desired transformation can quickly become a…

The Pd Catalyzed Amination Kits  are ideal tools for the investigation of cross-coupling reaction conditions. This enables to conveniently screen multiple reaction conditions simultaneously using pre-weighed catalysts and reagents. The kit contains all reagents and supplies to perform the…

Kit with PdOAc₂ with either AgF, SelectFluor, NFSI or TMPyF with or without PhIOPiv as oxidant 24 reaction vials totals.