Enzo Life Sciences

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  • MMP-12 Fluorescent Assay Kit, For Drug Discovery

    Enzo Life Sciences

    A QuantiZyme™ Assay System. The MMP-12 Fluorescent Assay Kit for Drug Discovery is a complete assay system designed to measure protease activity of matrix metalloproteinase-12 (MMP-12, metalloelastase, macrophage elastase) using a quenched fluorescent peptide: OmniMMP™ fluorescent…

  • Anatoxin A 1MG

    Enzo Life Sciences

  • Caspase-7, 5000 U

    Enzo Life Sciences

    >95% by SDS-PAGE, MW=20 + 12 kDa Storage: -80°C Caspase -7 1,2 is an effector caspase 3,4 in apoptosis with similar substrate preferences to caspase-3. Like caspase-3, it can cleave PARP-1 5-7 . It displays an affinity for ADP-ribose polymers and automodification of PARP-1…

  • Wortmannin

    Enzo Life Sciences

    98%, MW=428.4 [19545-26-7] Storage: -20°C Wortmannin, a fungal metabolite, is a potent and selective inhibitor of phosphatidylinositol 3-kinase 1 . It is active in purified preparations and cytosolic fractions (IC50=5 nM) and is highly cell permeable. It inhibits fMLP…

  • Phospholipase D 25 KU

    Enzo Life Sciences

  • Caspase-9, Caspase-9 Full Length

    Enzo Life Sciences

    >95% by SDS-PAGE, MW=20 + 12 kDa Storage: -80°C Caspase-9 is the initiator caspase of the mitochondrial/Apaf-1 apoptosis induction pathway 3-6 . This active caspase-9 (ICE-LAP-6; Mch6) is made from a human cDNA, expressed in E. coli. cDNA encodes residues identical to Ile-131 to…

  • Ly 294002

    Enzo Life Sciences

    2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 99%, MW=307.4 [154447-36-6] Storage: -20°C LY 294002 is a potent and specific cell-permeable inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase). In in vitro assays using purified PI 3-kinase, LY 294002 displays an IC50

  • Ag-825

    Enzo Life Sciences

    98%, MW=397.5, Storage: RT 5-[(Benzthiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide. A selective HER1-2 (HER2-Neu) 1 tyrosine kinase inhibitor 2 . 1. A. Levitzki et al., "Science" 1995, 267: 1782 2. H. Daub et al., "Nature" 1996, 379: 559

  • HBDDE

    Enzo Life Sciences

    97%, MW=338.4 Storage: -20°C 2,2',3,3'4,4'-Hexahydroxy-1,1'-biphenyl-6,6'-dimethanol dimethyl ether. Inhibits PKCα ; (IC50=43 µM) and PKCγ ; (IC50=50 µM) without inhibiting the δ , β I and β II isotypes 1 . 1. Y. Kashiwada et al., "J.…

  • Cyclosporin A

    Enzo Life Sciences

    >98%, MW=1202.6 [59865-13-3] Storage: -20°C Cyclosporin A (CsA) is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. CsA binds to cyclophilin and suppresses its proline rotamase activity. The CsA-cyclophilin complex…

  • Bapta, Free Acid

    Enzo Life Sciences

    97%, MW=476.4 [85233-19-8] Storage: -20°C 1,2-bis-(o-Aminophenoxy)-ethane-N,N,N',N'-tetraacetic acid. BAPTA is a Ca 2+ chelator with 105-fold greater affinity for Ca 2+ than for Mg 2+ 1,2 . BAPTA, free acid is not cell permeable and therefore is useful as an extracellular calcium…

  • U-0126

    Enzo Life Sciences

    98%, MW=380.5, Storage: RT A novel, potent and selective MEK inhibitor, MEK1 IC50=72 nM, MEK2 IC50=58 nM 1 . 1. M.F. Favata et al., "J. Biol. Chem." 1998, 273: 18623

  • Sb-203580

    Enzo Life Sciences

    98%, MW=377.4, Storage: -20°C 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole. Selective inhibitor of p38 mitogen-activated protein (MAP) kinase 1 . Inhibition is competitive with ATP (Ki=21 nM) 2 . Inhibits p38-MAPK stimulation of MAPKAPK2…

  • 5-Iodotubercidin

    Enzo Life Sciences

    98%, MW=392.2 [24386-93-4] Storage:-20°C Inhibits ERK2 (Ki= 525nM) 1 . also inhibits adenosine kinase (Ki= 30nM) CK1 and CK2 and insulin receptor kinase 2 . 1. T. Fox et al, "Protein Sci." 1998, 7: 2249 2. D. Massillon et al., "Biochem. J." 1994, 299: 123

  • S-Farnesyl-L-Cyst Me 25mg

    Enzo Life Sciences

  • AP4 50MG

    Enzo Life Sciences

  • MMP-3 Colorimetric Assay Kit, For Drug Discovery

    Enzo Life Sciences

    A QuantiZyme™ Assay System. The MMP-3 Colorimetric Assay Kit for Drug Discovery is a complete assay system designed to screen inhibitors of matrix metalloproteinase-3 (MMP-3, Stromelysin-1) using a thiopeptolide as a colorimetric substrate 1,2 . The MMP cleavage site peptide bond is replaced…

  • 1-ACYL-PAF 1MG

    Enzo Life Sciences

  • Spectinomycin 10g

    Enzo Life Sciences

  • 4-Phorbol 12-Myristate 13-Acetate (Pma)

    Enzo Life Sciences

    99%, MW=616.8 [63597-44-4] Storage: -20°C Negative control for phorbol 12-myristate 13-acetate (PMA).

  • 2-Aminopurine 100MG

    Enzo Life Sciences

  • Anti-Histone Deacetylase 1, 100 ug

    Enzo Life Sciences

    Rabbit polyclonal antibody Immunogen: C-terminal human HDAC1 (467-482) Supplied as epitope affinity purified IgG with 1 mg/ml BSA and 0.05% sodium azide in PBS. Recognizes human HDAC1 (approximately 62 kDa). Applications: Western Blotting 1/2000, Immunoprecipitation.

  • DAPI 10MG

    Enzo Life Sciences

    Item needs to be frozen and is available as DROP SHIP only.

  • Cyclo AAADPV 1MG

    Enzo Life Sciences

  • GAM-HRP 100µG

    Enzo Life Sciences

  • NFKB SN50 Pept 0.5mg

    Enzo Life Sciences

    Sequence contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NF-κB p50 linked to a peptide cell-permeablization sequence, the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF). Peptide inhibits…

  • RO 31-8220 1mg

    Enzo Life Sciences

  • MIT-E-PSI Mitochondrial Permeability Kit

    Enzo Life Sciences

    The Mit-E-ψ ™ Kit detects the change in mitochondrial permeability which is an early indication of the initiation of cellular apoptosis. The resulting change in membrane potential, (Δ ψ ) can be detected by a unique fluorescent cationic dye,…

  • RII Phosphopeptide, Calcineurin Substrate, 500 ug

    Enzo Life Sciences

    Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-pSer-Val-Ala-Ala-Glu >97%, MW=2192.0, Storage: -20°C Sequence is from cAMP-dependent protein kinase (PKA) regulatory subunit type II (RII), but with a phosphoserine at Ser-95. This peptide can be used directly as a calcineurin…

  • Hinokitiol 250 mg

    Enzo Life Sciences

  • Lufariellolide 1mg

    Enzo Life Sciences

  • CDP-Choline 1G

    Enzo Life Sciences

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