Specificity: Reacts with the heavy chain of human IgG Source: Pepsin digest of Goat Anti-Human IgG (SB Cat. No. 2040) Cross Adsorption: Human IgM and IgA; may react with IgG from other species Purification: Isotype: Goat F(ab')2 IgG Format/Conjugate: FITC (Fluorescein) Buffer…

The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin a4ß7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes but is also present on NK cells and eosinophils. The a4ß7 heterodimer mediates the binding of…

CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19…

Specificity: Reacts with the heavy and light chains of chicken IgY Source: Pooled antisera from goats hyperimmunized with IgY Cross Adsorption: None; may react with immunoglobulins from other species and the light chains of other chicken immunoglobulins Purification: Affinity…

Specificity: Reacts with mouse ? light chains Source: Pooled antisera from goats hyperimmunized with mouse ? light chains Cross Adsorption: Mouse ? light chains; may react with ? light chains from other species Purification: Affinity chromatography on mouse ? light chains covalently…

Specificity: Reacts with the heavy chain of mouse IgA Source: Pooled antisera from goats hyperimmunized with mouse IgA Cross Adsorption: Mouse IgG and IgM; may react with immunoglobulins from other species Purification: Affinity chromatography on mouse IgA covalently linked to agarose …

Specificity: Reacts with the heavy and light chains of rabbit IgG and the light chains of rabbit IgM Source: Pooled antisera from goats hyperimmunized with rabbit IgG Cross Adsorption: Mouse, rat, and human immunoglobulins and pooled sera; may react with immunoglobulins from other species …

Specificity: Reacts with the heavy and light chains of rat IgG and IgM Source: Pooled antisera from goats hyperimmunized with rat IgG and IgM Cross Adsorption: Mouse immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: Affinity chromatography on…

CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and…

Specificity: Reacts with mouse ? light chains Source: Pooled antisera from goats hyperimmunized with mouse ? light chains Cross Adsorption: Mouse ? light chains; may react with ? light chains from other species Purification: Affinity chromatography on mouse ? light chains covalently…

Specificity: Reacts with the heavy and light chains of human IgG and the light chains of human IgM and IgA Source: Pooled antisera from rabbits hyperimmunized with human IgG Cross Adsorption: None; may react with immunoglobulins from other species Purification: Affinity chromatography on…

Specificity: Reacts with the heavy and light chains of rabbit IgM and IgG Source: Pooled antisera from goats hyperimmunized with rabbit IgG Cross Adsorption: Human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: Affinity chromatography …

Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral…

Specificity: Reacts with the heavy and light chains of rabbit IgG and the light chains of rabbit IgM Source: Pooled antisera from goats hyperimmunized with rabbit IgG Cross Adsorption: Mouse and human immunoglobulins and pooled sera; may react with immunoglobulins from other species …

Ly-6G/Ly-6C, formerly known as the myeloid differentiation antigen Gr-1, is a GPI-anchored protein. In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation. It is also transiently expressed on monocytes in the bone marrow. In the…

CD45RB represents an exon B-dependent form of CD45 glycoprotein. It is expressed at high density on peripheral B cells, the suppressor/cytotoxic subpopulation of T lymphocytes, a subset of helper T cells, most thymocytes, and at low density on macrophages and dendritic cells.

Specificity: Reacts with the heavy chain of C57BL/6 mouse IgG2c Source: Pooled antisera from goats hyperimmunized with mouse IgG2c Cross Adsorption: Mouse IgG1, IgG2a, IgG2b, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species …

Specificity: Reacts with the heavy chain of mouse IgG3 Source: Pooled antisera from goats hyperimmunized with mouse IgG3 Cross Adsorption: Mouse IgG1, IgG2a, IgG2b, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …

Specificity: Reacts with the heavy chain of C57BL/6 mouse IgG2c Source: Pooled antisera from goats hyperimmunized with mouse IgG2c Cross Adsorption: Mouse IgG1, IgG2a, IgG2b, IgG3, IgM, and IgA; may react with immunoglobulins from other species Purification: Affinity chromatography on…

The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid…

The CD23 antigen is the low affinity IgE Fc receptor, which is a 45-49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells) and can also be found on the surface of T cells, macrophages and platelets. It is distinct from…

Specificity: Reacts with the heavy chain of mouse IgG2a Source: Pooled antisera from goats hyperimmunized with mouse IgG2a Cross Adsorption: Mouse IgG1, IgG2b, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …

CD81, also known as TAPA-1, is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of ?d+ T cells to more mature T cells…

Specificity: Reacts with the heavy and light chains of rat IgG and the light chains of rat IgM Source: Pepsin digest of Rabbit Anti-Rat IgG(H+L) (SB Cat. No. 6180) Cross Adsorption: None; may react with immunoglobulins from other species and the light chains of other rat immunoglobulins …

The monoclonal antibody DX5 reacts with CD49b, also known as very late antigen-2 (VLA-2) and a2 integrin. The antibody stains the majority of NK cells and a small subpopulation of T cells in all mouse strains tested (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, CBA/J,…

Specificity: Reacts with the heavy chain of rat IgG Source: Pooled antisera from goats hyperimmunized with rat IgG Cross Adsorption: Rat IgM; may react with immunoglobulins from other species Purification: Affinity chromatography on pooled rat IgG covalently linked to agarose Isotype: …

CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage),…

Specificity: Reacts with the heavy and light chains of mouse IgG and the light chains of mouse IgM and IgA Source: Pepsin digest of Rabbit Anti-Mouse IgG(H+L) (SB Cat. No. 6175) Cross Adsorption: Pooled human sera and immunoglobulins; may react with immunoglobulins from other species …

CD45 is the common leukocyte antigen and is expressed on all cells of hematopoietic origin except erythrocytes. CD45 exists as a number of different isoforms which result from alternative RNA splicing of exons 4, 5 and 6. The I3/2.3 monoclonal antibody recognizes a framework epitope present on all…

Specificity: Reacts with the heavy and light chains of goat IgG Source: Pooled antisera from donkeys hyperimmunized with goat IgG Cross Adsorption: Human, mouse, rat, hamster, rabbit, chicken, horse, and guinea pig serum proteins (SP); may react with immunoglobulins from other species and…