Separation Methods Technologies
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Specialty CIB-IgG Columns
Separation Methods TechnologiesSMT CIB-IgG are silica-based packing materials designed for for both high performance and low-pressure purification of protein A. In production of the IgG affinity-type columns, SMT utilizes its proprietary technique of self-assembled monolayer (SAM) of bonding to first immobilize unique mixed…
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Bulk SAX
Separation Methods TechnologiesSMT SAX Bulk Packings are silica-based Strong Anion eXchange packing developed for separation of anionic compounds. SMT SAX Bulk Packings consist of chemically attached hydrophilic surface derivatized to form quaternary amine. The technique of SAM is used in the bonding process to significantly…
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Reversed-Phase MEB4 Columns
Separation Methods TechnologiesSMT manufactures columns with short carbon chains for rapid analysis of basic, neutral, and mildly acidic drugs and small molecules. These columns provide excellent baseline resolution for small basic molecules including therapeutic drugs. The bonding scheme ensures proper deactivation substrate…
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Ion-Exchange SAX Columns
Separation Methods TechnologiesSMT-SAX columns are silica-based Strong Anion eXchange packing developed for separation of anionic compounds. SMT-SAX packings consist of chemically attached hydrophilic surface derivatized to form quaternary amine. The technique of SAM is used in the bonding process to significantly increase the…
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Normal Phase Aminopropyl Columns
Separation Methods TechnologiesSMT manufactures very stable aminopropyl [NH2] columns. SMT aminopropyl columns are often recommended for the separation of polar compounds and can be used in three separation modes: Normal Weak Anion Exchange Reversed-Phase In normal phase mode, the columns can be used to…
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Bulk Silica
Separation Methods TechnologiesSMT manufactures the most reliable silica based packing materials available in the market today. When silica is used as the stationary phase, the functional groups involved in separation are the surface silanols. However, metal impurities in silica may provide additional sites of interaction for…
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Ion-Exchange DEAE Columns
Separation Methods TechnologiesSMT-DEAE [Di-Ethyl-Amino-Ethyl] column provides a unique chemically attached hydrophilic, weak anion exchange type, functional surface desirable for the separation of many biomolecules such as proteins, nucleotides, oligonucleotides, polynucleotides, high molecular weight RNA?s and plasmid DNA?s.…
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Normal Phase Diol 1 Columns
Separation Methods TechnologiesSMT-Diol columns are developed as an alternative for silica columns used in normal phase separation methods. The Diol [-OH] functional group is controlled, and as such, provides more reproducible separation when compared to separation on silanols [-OH] from bare silica surface. Furthermore, the…
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Bulk C18
Separation Methods TechnologiesSMT manufactures the most reliable silica based octadecyl (C18) column available in the market today. This advanced new column is very stable at a wide pH range and high temperatures. SMT utilizes a proprietary bonding scheme that allows the resulting bonded phases to perform separation of basic,…
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Reversed-Phase MEB2 Columns
Separation Methods TechnologiesSMT manufactures columns with short carbon chains for rapid analysis of basic, neutral, and mildly acidic drugs and small molecules. These columns provide excellent baseline resolution for small basic molecules including therapeutic drugs. The bonding scheme ensures proper deactivation substrate…
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Bulk Aminopropyl
Separation Methods TechnologiesSMT manufactures very stable aminopropyl [NH2] packings. SMT aminopropyl columns are often recommended for the separation of polar compounds and can be used in three separation modes: Normal Weak Anion Exchange Reversed-Phase In normal phase mode, the columns can be used to…
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Specialty PAH Columns
Separation Methods TechnologiesPolyaromatic hydrocarbons (PAH?s) are large organic compounds produced during combustion. Many of these compounds are carcinogenic and are often found in water, air and other natural habitats. Monitoring of these compounds is very crucial for a healthy environment. The major challenge in HPLC…
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OL Series Reversed-Phase C8 Columns
Separation Methods TechnologiesOL Series SMT SAM-C8 phase with the lowest functional ligand coverage confirmed with carbon analysis results of 6% carbon load. In these series, the proportional ratio of the functional ligand, octyl or C8 molecule , mixed with the proprietary spacer molecule, is reduced. The result is a…
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Elite Series Reversed-Phase C8 Columns
Separation Methods TechnologiesElite-C18 Series: SMT SAM-C18 phases with the intermediate functional ligand coverage confirmed with carbon analysis results of 16% carbon load. In these series, the density of the functional ligand, octadecyl molecule or C18, is moderated with the proprietary spacer molecule to ensure maximum…
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Reversed-Phase C3 Columns
Separation Methods TechnologiesSMT SAM-C3 columns consist of Propyl as the functional ligand. The columns offer selectivities that are different from C8 and C18 reversed-phase columns when applied to separation of polyaromatic hydrocarbons. SMT-C3 columns are specially designed as complementary alternatives for the separation…
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Reversed-Phase MEB1 Columns
Separation Methods TechnologiesSMT manufactures columns with short carbon chains for rapid analysis of basic, neutral, and mildly acidic drugs and small molecules. These columns provide excellent baseline resolution for small basic molecules including therapeutic drugs. The bonding scheme ensures proper deactivation substrate…
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Specialty C12 Columns
Separation Methods TechnologiesSMT-C12 columns consist of Dodecyl as the functional ligand. The columns offer selectivities that are slightly different from C8 and C18 reversed-phase columns when applied to separation of polyaromatic hydrocarbons. SMT-C12 columns are specially designed as complementary alternatives for the…
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Normal Phase Cyanopropyl Columns
Separation Methods TechnologiesSMT manufactures ultra-stable cyanopropyl [CN] columns for normal and reversed-phase chromatographic separation modes. These columns have some special characteristics. When used in normal phase mode, with relatively nonpolar solvents, CN-stationary phase can separate many polar compounds just like…
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Elite Series Reversed-Phase C18 Columns
Separation Methods TechnologiesElite-C18 Series: SMT SAM-C18 phases with the intermediate functional ligand coverage confirmed with carbon analysis results of 16% carbon load. In these series, the density of the functional ligand, octadecyl molecule or C18, is moderated with the proprietary spacer molecule to ensure maximum…
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Specialty Chiral 1 Columns
Separation Methods TechnologiesChiral compounds, or enantiomers have identical molecular structures that are related as mirror images of one another much like a left hand is related to a right hand. Rapid and accurate stereochemical resolution of enantiomeric molecules has become a challenge in various aspects of pharmaceuticals…
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O Series Reversed-Phase C8 Columns
Separation Methods TechnologiesO Series SMT SAM-C8 phase with the highest functional ligand coverage confirmed with carbon analysis results of 12% carbon load. In these series, a very high density of the functional ligand, octyl molecule or C8, is achieved through meticulous mixture of the C8 with proprietary spacer…
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Bulk DEAE
Separation Methods TechnologiesSMT-DEAE [Di-Ethyl-Amino-Ethyl] column provides a unique chemically attached hydrophilic, weak anion exchange type, functional surface desirable for the separation of many biomolecules such as proteins, nucleotides, oligonucleotides, polynucleotides, high molecular weight RNA’s and plasmid…
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Bulk Diol 2
Separation Methods TechnologiesSMT-Diol bulk packings are developed as an alternative for silica bulk packings used in separation methods. The Diol [-OH] functional group is controlled, and as such, provides more reproducible separation when compared to separation on silanols [-OH] from bare silica surface. Furthermore, the…
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OD Series Reversed-Phase C18 Column
Separation Methods TechnologiesOD Series: SMT SAM-C18 phase with the highest functional ligand coverage confirmed with carbon analysis results of 24% carbon load. In these series, a very high density of the functional ligand, octadecyl (C18) molecule, is achieved through meticulous mixture of the C18 with proprietary spacer…
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Bulk C8
Separation Methods TechnologiesSMT manufactures the most reliable silica based octyl (C8) column available in the market today. This advanced new column is very stable at a wide pH range and high temperatures. SMT utilizes a proprietary bonding scheme that allows the resulting bonded phases to perform separation of basic,…
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Reversed-Phase Phenyl 1 Columns
Separation Methods TechnologiesSMT-Phenyl column provides unique selectivity for aromatic compounds when compared to other reversed-phase packings such as C18 and C8. The pie electrons of the phenyl group can interact with the aromatic ring of an analyte to increase retention relative to less or non-aromatic analytes. Unique…
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Bulk Cyanopropyl
Separation Methods TechnologiesSMT manufactures ultra-stable cyanopropyl [CN] packings for normal and reversed-phase chromatographic separation modes. These columns have some special characteristics. When used in normal phase mode, with relatively nonpolar solvents, CN-stationary phase can separate many polar compounds just like…
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Ion-Exchange WCX Columns
Separation Methods TechnologiesSMT-WCX columns are silica-based Weak Cation eXchange packing materials developed for separation of cationic compounds. SMT-WCX consists of chemically attached hydrophilic surface derivatized to form carboxylic acid functionality. The technique of SAM is used in the bonding process to significantly…
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Reversed-Phase Phenyl 2 Columns
Separation Methods TechnologiesSMT-Phenyl column provides unique selectivity for aromatic compounds when compared to other reversed-phase packings such as C18 and C8. The pie electrons of the phenyl group can interact with the aromatic ring of an analyte to increase retention relative to less or non-aromatic analytes. Unique…
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Reversed-Phase C5 Columns
Separation Methods TechnologiesSMT SAM-C5 columns consist of Pentyl as the functional ligand. The columns offer selectivities that are different from C8 and C18 reversed-phase columns when applied to separation of polyaromatic hydrocarbons. SMT-C5 columns are specially designed as complementary alternatives for the separation…
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AquSep Reversed-Phase C18 Columns
Separation Methods TechnologiesSMT AquSep is unique reversed phase packing material designed to have both hydrophobic and truly hydrophilic spacer ligands. The mixed-phase consists of a meticulously controlled mixture of hydrophobic, C18 molecules, and proprietary hydrophilic molecules, chemically attached on the silica…
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Specialty PFP Columns
Separation Methods TechnologiesSMT-C6F5 columns consist of Pentafluorophenyl as the functional ligand. The columns offer selectivities that are different from other reversed-phase columns when applied to separation of halogenated compounds, ketones, esters, and taxols. Taxol has been approved by the US Food and Drug…
