Viral Gene Delivery

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Viral Gene Delivery

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  • FGF2 shRNA lentivirus

    Cellomics Technology

    Fibroblast growth factor-2 (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 is a potent angiogenic growth factor. This lentivirus expresses…

  • Inducible tet-on NR2E3 lentivirus

    Cellomics Technology

    NR2E3, a photoreceptor-specific orphan nuclear receptor, is believed to play a pivotal role in the differentiation of photoreceptors. Mutations in NR2E3 result in syndromes characterized by excess blue cones and loss of rods: enhanced S-cone syndrome (ESCS). This lentivirus expresses human NR2E3…

  • CMV-LacZ lentivirus

    Cellomics Technology

    LacZ catalyzes the hydrolysis of the disaccharide lactose, into gluclose and galactose. The use of LacZ as a reporter gene is due to its ability to cleave the bond between galactose and the indole, 5-bromo-4-chloro-3-hydroxyindole. The cleaved indole, is an easily detectable and insoluble blue compound.

  • hTERT lentivirus (CMV, Puro)

    Cellomics Technology

    Telomerase reverse transcriptase (TERT, or hTERT in human) is a catalytic subunit of the enzyme telomerase, Ectopic expression of telomerase in telomerase-silent cells is sufficient to overcome senescence and to extend cellular lifespan, and has been used for cell immortalization. This lentivirus…

  • Inducible tet-on Smad6 lentivirus

    Cellomics Technology

    Smad6 and Smad7 are inhibitory Smads induced by transforming growth factor β-Smad signal transduction pathways in a negative-feedback mechanism. Smad6 promotes neuronal differentiation in the intermediate zone of the dorsal neural tube. Smad6 is also involved in multiple tissue differentiation…

  • miR-302 is the major microRNA (mRNA) found in human embryonic stem cells and induced pluripotent stem cells.

  • CMV-Cre lentivirus

    Cellomics Technology

    Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • Inducible tet-on ASCL1 lentivirus

    Cellomics Technology

    ASCL1 (Achaete-Scute Family BHLH Transcription Factor 1) is a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding.…

  • CXCL1 shRNA lentivirus

    Cellomics Technology

    In humans, CXCL1 gene encodes a small chemokine (C-X-C motif) ligand 1 (CXCL1) cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). CXCL1 plays…

  • Capo Transfection Kit

    Oz Biosciences

    Calcium Phosphate (CaPO) Transfection Kit is perfect to transfect HEK 293 cells. This transfection method, first described by Graham and Van Der Ebb in 1973, has been optimized in order to reach higher transfection efficiency. The CaPO transfection kit is simple and easy to use. It allows reaching…

  • This NF-kB reporter lentivirus expresses Firefly luciferase under the control of a minimal (m)CMV promoter and tandem repeats of the NF-kB transcriptional response element (TRE). It can be used to monitor the transcriptional activity of NF-kB.

  • Inducible tet-on CRX lentivirus

    Cellomics Technology

    CRX is a homeodomain transcription factor and one of the key regulator genes of photoreceptor formation. CRX play an important role in transdifferentiation of photoreceptor cells. This lentivirus expresses human Crx under the control of the Tet promoter.

  • CMV-MAD2 lentivirus

    Cellomics Technology

    MAD2 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2 was showed to be associated with tumor differentation. This lentivirus express human MAD2 under the control of the CMV promoter.

  • EF1A-miR-211 lentivirus

    Cellomics Technology

    It has been observed that microRNA (mRNA) miR-211 plays a role in the regulation of cancer metastasis. This lentivirus expresses miR-211 under the control of the EF1A promoter.

  • CMV-Cre-GFP lentivirus

    Cellomics Technology

    Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • CMV-RFP lentivirus

    Cellomics Technology

    TurboRFP is a red (orange) fluorescent protein (ex. 553 and em. 574 nm) derived from sea anemoneEntacmaea quadricolor [Merzlyak et al., 2007]. Possessing high photostability and pH stability, TurboRFP is more than twice brighter than DsRed2. Fast TurboRFP maturation makes it clearly detectable in…

  • CMV-OTX2 lentivirus

    Cellomics Technology

    OTX2 is a homeodomain transcription factor and one of the key regulator genes of photoreceptor formation. This lentivirus expresses human OTX2 under the control of the CMV promoter.

  • This set contains six EF1A-driven vectors: LIN28 (PLV-10015), NANOG (PLV-10014), SOX2 (PLV-10013), OCT3/4 (PLV-10012), KLF4 (PLV-10011) and C-MYC (PLV-10010). Human elongation factor-1 alpha (EF-1 alpha) is a constitutive promoter of human origin that can be used to drive ectopic gene expression in…

  • CMV-GFP lentivirus

    Cellomics Technology

    Green fluorescent protein (GFP), a 27 kDa protein derived from the jellyfish Aequorea victoria, emits green light (emission peak at a wavelength of 509 nm) when excited byblue light (excitation peak at a wavelength of 395 nm). Green Fluorescent Protein (GFP) has become an invaluable tool in cell…

  • In Vivo Polymag

    Oz Biosciences

    In vivo PolyMag™ Transfection Reagent has been designed for in vivo targeted transfection of various types of nucleic acids such as DNA, RNA, oligonucleotides using magnetic nanoparticles coated with specific polymers. DNA complexes can be easily administrated through various injection routes…

  • Luciferase is an enzyme that is catalyzes the oxidation of luciferin to generate bioluminescence. Firefly luciferase refers to the enzyme that was isolated from Photinus pyralis. This lentivirus coexpresses Firefly luciferase and puromycin driven by the CMV promoter, allowing generation of Firefly…

  • Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • Inducible tet-on RORB lentivirus

    Cellomics Technology

    RAR-related orphan receptor B (RORB) is a member of the NR1 subfamily of nuclear hormone receptors. Rorb has been shown to be involved in the differentiation of rod photoreceptor cells, Amacrine and horizontal interneurons and associated with bipolar disorder. This lentivirus expresses human RORB…

  • Luciferase is an enzyme that is catalyzes the oxidation of luciferin to generate bioluminescence. Firefly luciferase refers to the enzyme that was isolated from Photinus pyralis. This lentivirus expresses Firefly luciferase under the control of CMV promoter.

  • The ViraTrap™ retrovirus mini purification kit is designed for fast and efficient purification of recombinant retroviruses from retrovirus-transfected cell culture supernatant. Up to 3 x10 12 viral particles can be purified from cell culture media of 1 to 2 T75 flasks. Traditionally the…

  • The ViraTrap™ adenovirus mini purification kit is designed for fast and efficient purification of recombinant Adenovirus from adenovirus transfected cell culture supernatant. Up to 1 x10 12 viral particles can be purified from cell culture media of 1 to 2 T75 flasks. Traditionally the…

  • Calcium is a universal second messenger regulating essential cellular signaling events in a broad range of tissues and organisms. GCaMP3 is a fusion calcium indicator of green fluorescent protein (GFP), calmodulin and the M13 domain of a myosin light chain kinase designed to show the calcium ion…

  • Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • CIAPIN1 shRNA lentivirus

    Cellomics Technology

    In humans, CIAPIN1 (Cytokine Induced Apoptosis Inhibitor 1) encodes a protein called Anamorsin. Expression of CIAPIN1 is dependent on growth factor stimulation. It has no relationship to apoptosis regulatory molecules of the BCL2 or CASP families. Its related pathways include Metabolism and…

  • CMV-TNFSF12 lentivirus

    Cellomics Technology

    TNFSF12 is a member of the tumor necrosis factor (TNF) ligand family. TNFSF12 is a ligand for the FN14/TWEAKER receptor involved in apoptosis and angiogenesis. This lentivirus expresses human TNFSF12 under the control of the CMV promoter.

  • EF1A-SOX2 lentivirus

    Cellomics Technology

    SRY (sex determining region Y)-box 2 (SOX2) is a transcription factor critical for maintaining the self-renewal capacity of undifferentiated stem cells. Ectopic expression of SOX2 has been used to produce iPS cells in culture. Human elongation factor-1 alpha (EF-1 alpha) is a constitutive…

  • ADAM-17 shRNA lentivirus

    Cellomics Technology

    ADAM-17 gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM-17 is an…

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