Viral Gene Delivery

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Viral Gene Delivery

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  • Inducible tet-on Ars2 lentivirus

    Cellomics Technology

    Ars2 (arsenite-resistance protein 2; also known as Srrt) is a highly conserved zinc finger protein. Ars2 is necessary and sufficient to promote NSC (neural stem cells) self-renewal. This premade lentivirus expresses Ars2 under the control of Tet promoter.

  • Inducible tet-on RORB lentivirus

    Cellomics Technology

    RAR-related orphan receptor B (RORB) is a member of the NR1 subfamily of nuclear hormone receptors. Rorb has been shown to be involved in the differentiation of rod photoreceptor cells, Amacrine and horizontal interneurons and associated with bipolar disorder. This lentivirus expresses human RORB…

  • The ViraTrap™ lentivirus mini purification kit is designed for fast and efficient purification of recombinant lentiviruses from lentiviral-transfected cell culture supernatant. Viral particles can be purified from cell culture of 4 to 5 T75 flasks per column. The viruses are first applied…

  • EF1A-GFP lentivirus

    Cellomics Technology

    Green fluorescent protein (GFP), a 27 kDa protein derived from the jellyfish Aequorea victoria, emits green light (emission peak at a wavelength of 509 nm) when excited byblue light (excitation peak at a wavelength of 395 nm). Green Fluorescent Protein (GFP) has become an invaluable tool in cell…

  • Inducible tet-on KLF4 lentivirus

    Cellomics Technology

    Krueppel-like factor 4 (KLF4) is a zinc finger transcriptional regulator that has been identified as a good indicator of stem cell-like capacity and is subsequently used in iPS cell generation. KFL4 plays an important role in maintaining stem cells, and in preventing their differentiation. This…

  • Luciferase is an enzyme that is catalyzes the oxidation of luciferin to generate bioluminescence. Firefly luciferase refers to the enzyme that was isolated from Photinus pyralis.

  • EF1A-OCT3/4 lentivirus

    Cellomics Technology

    OCT3/4 (POU5F1) is a transcription factor that is expressed in stem cells and germ cells. Its expression is required to sustain cell self-renewal of undifferentiated stem cells. Oct-3/4 is the most recognized marker for totipotent ES cells. Ectopic expression of OCT3/4 has been used to produce iPS…

  • HPSE shRNA lentivirus

    Cellomics Technology

    Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix.Heparanase (HPSE) is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. HPSE is critical regulator of angiogenesis and tumor…

  • Inducible tet-on Hnf4a lentivirus

    Cellomics Technology

    Hnf4a is a nuclear transcription factor which binds DNA as a homodimer. Hnf4a controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver,…

  • CMV-MAD2 lentivirus

    Cellomics Technology

    MAD2 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2 was showed to be associated with tumor differentation. This lentivirus express human MAD2 under the control of the CMV promoter.

  • Inducible tet-on Chx10 lentivirus

    Cellomics Technology

    The homeodomain transcription factor Chx10 is one of the earliest markers of the developing retina. It is required for retinal progenitor cell proliferation as well as formation of bipolar cells, a type of retinal interneuron.

  • The ViraTrap™ retrovirus mini purification kit is designed for fast and efficient purification of recombinant retroviruses from retrovirus-transfected cell culture supernatant. Up to 3 x10 12 viral particles can be purified from cell culture media of 1 to 2 T75 flasks. Traditionally the…

  • UBC-Cre-RFP lentivirus

    Cellomics Technology

    Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • Luciferase is an enzyme that is catalyzes the oxidation of luciferin to generate bioluminescence. Firefly luciferase refers to the enzyme that was isolated from Photinus pyralis. This lentivirus coexpresses Firefly luciferase and puromycin driven by the CMV promoter, allowing generation of Firefly…

  • OTX2 is a homeodomain transcription factor and one of the key regulator genes of photoreceptor formation. This lentivirus expresses human OTX2 under the control of the Tet promoter.

  • Inducible tet-on Smad6 lentivirus

    Cellomics Technology

    Smad6 and Smad7 are inhibitory Smads induced by transforming growth factor β-Smad signal transduction pathways in a negative-feedback mechanism. Smad6 promotes neuronal differentiation in the intermediate zone of the dorsal neural tube. Smad6 is also involved in multiple tissue differentiation…

  • Luciferase is an enzyme that is catalyzes the oxidation of luciferin to generate bioluminescence. Firefly luciferase refers to the enzyme that was isolated from Photinus pyralis. This lentivirus expresses Firefly luciferase under the control of CMV promoter.

  • It has been observed that microRNA miR-204 plays a role in the regulation of cancer metastasis. This lentivirus expresses miR-204 under the control of the Tet promoter.

  • ANGPTL4 shRNA lentivirus

    Cellomics Technology

    ANGPTL4 gene encodes a glycosylated, secreted Angiopoietin-like 4 protein containing a C-terminal fibrinogen domain. The encoded protein plays an critical role in numerous cancers and it is implicated in the metastatic process by modulating vascular permeability, cancer cell motility and…

  • EF1A-HLF lentivirus

    Cellomics Technology

    Hepatic Leukemia Factor (HLF) is a member of the proline and acidic-rich (PAR) family, a subset of the bZIP transcription factors. Chromosomal translocation of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemia. This lentivirus expresses human HLF under the…

  • Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • CMV-GFP lentivirus

    Cellomics Technology

    Green fluorescent protein (GFP), a 27 kDa protein derived from the jellyfish Aequorea victoria, emits green light (emission peak at a wavelength of 509 nm) when excited byblue light (excitation peak at a wavelength of 395 nm). Green Fluorescent Protein (GFP) has become an invaluable tool in cell…

  • The ViraTrap™ Adenovirus maxi purification kit is designed for fast and efficient purification of recombinant Adenovirus from adenovirus transfected cell culture supernatant. Up to 4 x10 12 viral particles can be purified from cell culture media of 6 to 8 T75 flasks. Traditionally the…

  • The ViraTrap™ adenovirus mini purification kit is designed for fast and efficient purification of recombinant Adenovirus from adenovirus transfected cell culture supernatant. Up to 1 x10 12 viral particles can be purified from cell culture media of 1 to 2 T75 flasks. Traditionally the…

  • CAG-GFP lentivirus

    Cellomics Technology

    Green fluorescent protein (GFP), a 27 kDa protein derived from the jellyfish Aequorea victoria, emits green light (emission peak at a wavelength of 509 nm) when excited byblue light (excitation peak at a wavelength of 395 nm). Green Fluorescent Protein (GFP) has become an invaluable tool in cell…

  • BrainFectIN™ enables nucleic acids delivery into central nervous system of small animals. Major difficulties with gene delivery in the central nervous system is the weakness of standard non-viral gene carriers and the limitations associated to the use of viral particles (time-consuming and…

  • Inducible tet-on C-MYC lentivirus

    Cellomics Technology

    MYC (C-MYC) is a regulator gene that codes for a transcription factor is believed to regulate expression of 15% of all genes. C-MYC is one of the genes that has been used to generate iPS cells in culture. This lentivirus expresses C-Myc under the control of the Tet promoter.

  • CMV-Pax6 lentivirus

    Cellomics Technology

    Pax6 (paired box 6) is a transcriptional regulator with paired box domain and homeo box domain. Pax6 is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. This lentivirus expresses…

  • EF1A-NANOG_m lentivirus

    Cellomics Technology

    NANOG is a transcription factor important for maintaining the self-renewal capacity of undifferentiated stem cells. Ectopic expression of NANOG has been used to generate iPS cells in culture. Human elongation factor-1 alpha (EF-1 alpha) is a constitutive promoter of human origin that can be used…

  • CMV-Cre-GFP lentivirus

    Cellomics Technology

    Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • Inducible tet-on CRX lentivirus

    Cellomics Technology

    CRX is a homeodomain transcription factor and one of the key regulator genes of photoreceptor formation. CRX play an important role in transdifferentiation of photoreceptor cells. This lentivirus expresses human Crx under the control of the Tet promoter.

  • Inducible tet-on Brn2 lentivirus

    Cellomics Technology

    BRN2 (also known as POU3F2) encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an…

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