Viral Gene Delivery

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Viral Gene Delivery

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  • CMV-N-MYC lentivirus

    Cellomics Technology

    MYC is a regulator gene that codes for a transcription factor is believed to regulate expression of 15% of all genes. Amplification of N-Myc is associated with a variety of tumors, most notably neuroblastomas. N-Myc is one of the genes that has been used to generate iPS cells in culture.

  • HIF1A shRNA lentivirus

    Cellomics Technology

    HIF1A gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes,…

  • EF1A-C-MYC lentivirus

    Cellomics Technology

    MYC (C-MYC) is a regulator gene that codes for a transcription factor is believed to regulate expression of 15% of all genes. C-MYC is one of the genes that has been used to generate iPS cells in culture. Human elongation factor-1 alpha (EF-1 alpha) is a constitutive promoter of human origin…

  • CMV-LHX2 lentivirus

    Cellomics Technology

    LHX2 (LIM Homeobox 2) belongs to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. LHX2 is involved in neuronal differentiation. This lentivirus expresses human LHX2 under the control of the CMV promoter.

  • HPSE shRNA lentivirus

    Cellomics Technology

    Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. Heparanase (HPSE) is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. HPSE is critical regulator of angiogenesis and…

  • ViraTrap™ Adenovirus Purification Maxi Kits

    Biomiga

    The ViraTrap™ Adenovirus maxi purification kit is designed for fast and efficient purification of recombinant Adenovirus from adenovirus transfected cell culture supernatant. Up to 4 x10 12 viral particles can be purified from cell culture media of 6 to 8 T75 flasks. Traditionally the…

  • UBC-GFP lentivirus

    Cellomics Technology

    Green fluorescent protein (GFP), a 27 kDa protein derived from the jellyfish Aequorea victoria, emits green light (emission peak at a wavelength of 509 nm) when excited byblue light (excitation peak at a wavelength of 395 nm). Green Fluorescent Protein (GFP) has become an invaluable tool in cell…

  • hTERT lentivirus (CMV, Puro)

    Cellomics Technology

    Telomerase reverse transcriptase (TERT, or hTERT in human) is a catalytic subunit of the enzyme telomerase, Ectopic expression of telomerase in telomerase-silent cells is sufficient to overcome senescence and to extend cellular lifespan, and has been used for cell immortalization. This lentivirus…

  • CMV-Cre lentivirus

    Cellomics Technology

    Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • ViraTrap™ Lentivirus Purification Mini Kits

    Biomiga

    The ViraTrap™ lentivirus mini purification kit is designed for fast and efficient purification of recombinant lentiviruses from lentiviral-transfected cell culture supernatant. Up to 3x10 10 viral particles can be purified from cell culture media of 1 to 2 T75 flasks. The viruses are first…

  • Inducible tet-on SOX9 lentivirus

    Cellomics Technology

    SOX9 is a transcription factor essential for multipotent neural stem cell (NSC) formation and maintenance. Sox9 is a major molecular component of the neuron–glia switch in the developing spinal cord. SOX9 also plays a key role in chondrogenesis. This lentivirus expresses human SOX9 under the…

  • CMV-RAX lentivirus

    Cellomics Technology

    RAX (Retina And Anterior Neural Fold Homeobox) is a homeobox-containing transcription factor that functions in eye development. RAX is required for retinal cell fate determination and also regulates stem cell proliferation. Mutations in this gene have been reported in patients with defects in…

  • Inducible tet-on FOXD1 lentivirus

    Cellomics Technology

    Forkhead transcription factors are essential for diverse processes in early embryonic development and organogenesis. Foxd1 plays a dual role in the establishment of the binocular visual pathways: specification of the ventrotemporal (VT) retina, and patterning of the developing ventral diencephalon…

  • Inducible tet-on miR-200b,a, 429 lentivirus

    Cellomics Technology

    The miR-200 family (miR-200a, -200b, -200c, -141 and -429) and miR-205 are frequently silenced in advanced cancer and have been implicated in epithelial to mesenchymal transition (EMT) and tumor invasion by targeting the transcriptional repressors of E-cadherin, ZEB1 and ZEB2.

  • EF1A-Vector Control lentivirus

    Cellomics Technology

    This is a vector control for our EF1A lentiviral vectors.

  • Inducible tet-on miR-204 lentivirus

    Cellomics Technology

    It has been observed that microRNA miR-204 plays a role in the regulation of cancer metastasis. This lentivirus expresses miR-204 under the control of the Tet promoter.

  • Inducible tet-on OCT3/4 lentivirus

    Cellomics Technology

    OCT3/4 (POU5F1) is a transcription factor that is expressed in stem cells and germ cells. Its expression is required to sustain cell self-renewal of undifferentiated stem cells. Oct-3/4 is the most recognized marker for totipotent ES cells. Ectopic expression of OCT3/4 has been used to produce iPS…

  • EF1A-NANOG_m lentivirus

    Cellomics Technology

    NANOG is a transcription factor important for maintaining the self-renewal capacity of undifferentiated stem cells. Ectopic expression of NANOG has been used to generate iPS cells in culture. Human elongation factor-1 alpha (EF-1 alpha) is a constitutive promoter of human origin that can be used…

  • CMV-Pax6 lentivirus

    Cellomics Technology

    Pax6 (paired box 6) is a transcriptional regulator with paired box domain and homeo box domain. Pax6 is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. This lentivirus expresses…

  • CMV-Vector Control lentivirus

    Cellomics Technology

    This is a vector control for our CMV lentiviral vectors.

  • ViraTrap™ Retrovirus Purification Maxi Kits

    Biomiga

    The ViraTrap™ retrovirus maxi purification kit is designed for fast and efficient purification of recombinant retroviruses from retrovirus-transfected cell culture supernatant. Up to 1 x10 13 viral particles can be purified from cell culture media of 6 to 8 T75 flasks. Traditionally the…

  • Inducible tet-on SOX2 lentivirus

    Cellomics Technology

    SRY (sex determining region Y)-box 2 (SOX2) is a transcription factor critical for maintaining the self-renewal capacity of undifferentiated stem cells. Ectopic expression of SOX2 has been used to produce iPS cells in culture. This lentivirus expresses Sox2 under the control of the Tet promoter.

  • Angiopoietin-1 (Angpt1) shRNA lentivirus

    Cellomics Technology

    Angpt1 gene encodes a secreted glycoprotein called Angiopoietin 1 that activates the receptor by inducing its tyrosine phosphorylation. It appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. It may also mediate blood…

  • Inducible tet-on GFP lentivirus

    Cellomics Technology

    Green fluorescent protein (GFP), a 27 kDa protein derived from the jellyfish Aequorea victoria, emits green light (emission peak at a wavelength of 509 nm) when excited by blue light (excitation peak at a wavelength of 395 nm). Green Fluorescent Protein (GFP) has become an invaluable tool in cell…

  • ViraTrap™ Adenovirus Purification Mini Kits

    Biomiga

    The ViraTrap™ adenovirus mini purification kit is designed for fast and efficient purification of recombinant Adenovirus from adenovirus transfected cell culture supernatant. Up to 1 x10 12 viral particles can be purified from cell culture media of 1 to 2 T75 flasks. Traditionally the…

  • ViraTrap™ Retrovirus Purification Mini Kits

    Biomiga

    The ViraTrap™ retrovirus mini purification kit is designed for fast and efficient purification of recombinant retroviruses from retrovirus-transfected cell culture supernatant. Up to 3 x10 12 viral particles can be purified from cell culture media of 1 to 2 T75 flasks. Traditionally the…

  • UBC-Firefly luciferase lentivirus (Neo)

    Cellomics Technology

    Luciferase is an enzyme that is catalyzes the oxidation of luciferin to generate bioluminescence. Firefly luciferase refers to the enzyme that was isolated from Photinus pyralis. This lentivirus expresses Firefly luciferase under the control of UBC promoter.

  • Inducible tet-on C-MYC lentivirus

    Cellomics Technology

    MYC (C-MYC) is a regulator gene that codes for a transcription factor is believed to regulate expression of 15% of all genes. C-MYC is one of the genes that has been used to generate iPS cells in culture. This lentivirus expresses C-Myc under the control of the Tet promoter.

  • Inducible tet-on PAX6 lentivirus

    Cellomics Technology

    Pax6 gene contains a paired domain and a paired-type homeodomain and is expressed during early neuroretina development. Pax6 is required for multipotency of retinal progenitors. Tansfection of Pax6 into ES or iPS cells induces retinal progenitors. Pax6 alone is sufficient to induce…

  • CHI3L1 shRNA lentivirus

    Cellomics Technology

    In humans, CHI3L1 encodes Chitinase-3-like protein 1 (CHI3L1) that a glycoprotein member of the glycosyl hydrolase 18 family. It is a secreted glycoprotein and catalyzes the hydrolysis of chitin glycopolymer found in insect exoskeletons and fungal cell walls. The protein lacks chitinase activity…

  • Inducible tet-on PKNOX2 lentivirus

    Cellomics Technology

    PKNOX2 belongs to the three amino acid loop extension (TALE) superclass of homeodomain-containing proteins and encodes a polypeptide of 462 residues. Studies showed PKNOX2 might be involved in the regulation of limb zeugopod and deltoid crest development.

  • Inducible tet-on NR2E3 lentivirus

    Cellomics Technology

    NR2E3, a photoreceptor-specific orphan nuclear receptor, is believed to play a pivotal role in the differentiation of photoreceptors. Mutations in NR2E3 result in syndromes characterized by excess blue cones and loss of rods: enhanced S-cone syndrome (ESCS). This lentivirus expresses human NR2E3…

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