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  • Glucagon is a single-chain polypeptide that contains 29 amino acid residues and has a molecular weight of 3,483. Glucagon is a hormone produced in the pancreas and it is used to raise very low blood sugar. Glucagon is also used in diagnostic testing of the stomach and other digestive organs. …

  • PreScission Protease is a fusion protein of glutathione S-transferase (GST) and human rhinovirus (HRV) type 14 3C protease . The protease specifically recognizes a subset of sequences which include the core amino acid sequence Leu-Phe-Gln/Gly-Pro cleaving between the Gln and Gly residues .…

  • PTH (7-34aa) Human

    GenScript

    Polypeptide hormones secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and…

  • 10 mM Stabilized dNTP mix (HS dNTP Mix) is suitable for use in PCR, sequencing, nick translation, fill-in, cDNA synthesis, TdT tailing reactions, and dilution of radiolabeled dNTPs. These nucleotides are supplied as convenient, ready-to-use solutions at a concentration of 10 mM in Tris-HCl (pH…

  • Receptor activity-modifying proteins (RAMPs) are a class of protein which interact with and modulate the activities of several Class B G Protein-Coupled Receptors including the receptors for secretin, calcitonin (CT), glucagon, and vasoactive intestinal peptide (VIP).There are three distinct types…

  • Tyrosinase (369-377,YMDG™SQV) is derived from the membrane protein tyrosinase by posttranslational conversion of the sequence YMNG™SQV. Presentation of YMDG™SQV in cells expressing full-length tyrosinase is TAP-(transporter associated with antigen processing) and proteosome-dependent.

  • DKK-1, Human

    GenScript

    Dickkopf related protein 1 (DKK-1) is a chemokine that belongs to the DKK protein family, which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. It is one of the most up-regulated genes during…

  • The Western Wash Box, made of durable AS plastic, is designed for use with western blots. These boxes are resistant to acid, alkali and organic ingredients. You will find them a reliable and convenient addition to your experiment.

  • HB-EGF, Human

    GenScript

    Proheparin-binding EGF-like growth factor (HB-EGF), also known as DTR, DTS and HEGFL, is a member of the EGF family of mitogens. It is expressed in macrophages, monocytes, endothelial cells and muscle cells. HB-EGF signals through the EGF receptor to stimulate the proliferation of smooth muscle…

  • Growth hormone releasing peptide (GHRP) was studied in rats and produced a large plasma GH response in the presence of exogenous GH-releasing factor. This response was significantly augmented when somatostatin-antiserum was present. This peptide could be an alternative therapeutic agent in GH therapy.

  • Fibroblast Growth Factor Receptor-1 (FGFR-1) is a transmembrane tyrosine kinase receptor belonging to the FGFR family. FGFR family has 4 members, FGFR-1 to FGFR-4, and they all have similar structural characteristics with 3 extracellular immunoglobulin-like (Ig) domains. FGFRs bind to FGFs with…

  • The nonapeptide 149,YFPGQFAFS157 (chemerin-9), corresponding to the C terminus of processed chemerin, retained most of the activity of the full-size protein, with regard to agonism toward the chemerinR.the natural ligand of ChemR23 (chemerinR).

  • TWEAK, Human

    GenScript

    TWEAK, short for TNF-related weak inducer of apoptosis, is also known as TNFSF12 and DR3LG. It is a type II transmembrane protein belonging to the TNF superfamily. It is expressed widely in many tissues, such as the heart, skeletal muscle, spleen and peripheral blood. Binding of TWEAK to its…

  • The corticotropin-releasing factor receptor 2 CRF2 is Gs-coupled GPCRs expressed in the brain, blood vessels and intestine that bind to corticotropin-releasing factor (CRF). The CRF is a 41-amino acid peptide that plays an important role in the integration of autonomic, neuroendocrine, and…

  • Goat Anti-Swine IgG (H&L) antibody Texas Red® conjugated, pAb. This product is designed for immunofluorescence microscopy, fluorescence based plate assays (FLISA) and fluorescent western blotting. This product is also suitable for multiplex analysis, including multicolor imaging, utilizing…

  • GenScript ExpressPlus™ PAGE Gels are high-performance precast mini polyacrylamide gels specially designed for large loading volumes. The unique design of the cassette gives better band resolution and significantly improves the sample distribution in the loading wells which increases the…

  • CTLA4 or CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152 (cluster of differentiation 152), is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses. CTLA4 is constitutively expressed in Tregs but only upregulated in conventional T…

  • Arg-Gly-Glu-Ser

  • MCP-1/CCL2, Rat

    GenScript

    Chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemotactic protein 1 (MCP1) and small inducible cytokine A2. CCL2 is a small cytokine that belongs to the CC chemokine family. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced…

  • The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for…

  • SAMs Peptide,0.5mg

    GenScript

    SAMs Peptide is a modified version of the sequence around the AMPK target site in rat acetyl-CoA carboxylase. It is widely used as a substrate for AMP-activated protein kinase (AMPK). Phosphorylated rapidly by AMPK, SAMs Peptide is more specific for the kinase than acetyl CoA carboxylase itself,…

  • Rabbit Anti-Human IgG (H&L) antibody Unconjugated, pAb.

  • GenScript ExpressPlus™ PAGE Gels are high-performance precast mini polyacrylamide gels specially designed for large loading volumes. The unique design of the cassette gives better band resolution and significantly improves the sample distribution in the loading wells which increases the…

  • HB-EGF, Human

    GenScript

    Proheparin-binding EGF-like growth factor (HB-EGF), also known as DTR, DTS and HEGFL, is a member of the EGF family of mitogens. It is expressed in macrophages, monocytes, endothelial cells and muscle cells. HB-EGF signals through the EGF receptor to stimulate the proliferation of smooth muscle…

  • Goat Anti-Monkey IgA antibody Fluorescein (FITC) conjugated, pAb. This product is designed for immunofluorescence microscopy, fluorescence based plate assays (FLISA) and fluorescent western blotting. This product is also suitable for multiplex analysis, including multicolor imaging, utilizing…

  • Gastrin-1 (human), which is mainly expressed in the gut, activates gastric acid secretion and stimulates lectin-like protein Reg expression via activation of PKC and RhoA. It is used as a marker for gastritis.

  • IGF-II, Human

    GenScript

    Insulin-like Growth Factor II (IGF-II) is a single chain 7 kDa polypeptide, and shares a high degree of homology with insulin. During circulation in vivo, IGF-II is complexed to high affinity binding proteins, IGF Binding Proteins (IGFBP), which act as circulating reservoirs, transport IGF-II,…

  • The gonadotropin-releasing hormone receptor (GNRHR), also known as the luteinizing hormone releasing hormone receptor (LHRHR), is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes,…

  • Cluster of Differentiation 80 (also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular…

  • IL-31, Human

    GenScript

    Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong…

  • Secretoneurin (Rat) is a neuropeptide generated in brain, adrenal medulla and other endocrine tissues by proteolytic processing of secretogranin II (chromogranin C). The endogenous peptide can enhance dopamine release.

  • Protein A, a bacterial cell wall protein isolated from Staphylococcus aureus, binds to mammalian IgGs mainly through Fc regions. The Protein A is most commonly bound to a chromatography resin, used for production of antibody drugs or reagents. Protein A antibody can be used for quantification of…

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