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  • An LRF-amide motif containing fragment of malignant melanoma metastasis-suppressor KiSS-1 which binds to human GPR54, a G-protein-coupled receptor also known as AXOR12. It shows lower agonistic potency towards AXOR12 than malignant melanoma metastasis-suppressor Kisspeptin-10 (H-5544).

  • H-7442 was obtained by dissolving Amyloid β-Protein (1-42) (H-1368) in HFIP, aliquoting, and removing the solvent as described in the literature.

  • Cecropin A (1-7)-Melittin A (2-9) amide, also referred to as CAMEL0, is a synthetic hybrid peptide that is composed of portions of the naturally occurring antibiotic peptide cecropin A and melittin. CAMEL0 shows a better antimicrobial activity than the native molecules, but lacks the hemolytic…

  • Somatostatin analog for tumor scintigraphy and radionuclide therapy.

  • Heavy isotope-labeled octreotide useful for pharmacokinetic/pharmacodynamic studies in combination with Bachem product H-5972 Octreotide and the corresponding API, H-5972-GMP.

  • Aβ 1-42, 42-residue fragment of amyloid precursor protein, has been found to be a major constituent of the senile plaques formed in the brains of patients with Alzheimer's disease and late Down's syndrome. Aβ 1-42 readily forms neurotoxic oligomers at physiological pH. On the…

  • Cecropin B

    Bachem

    Cecropin B is a 35-residue peptide which showed activity against different tumor cell lines.

  • Octreotide

    Bachem

    A slow-release form of octreotide. Pamoate is the bivalent anion of pamoic acid (embonic acid, 4,4·-methylene-bis-(3-hydroxy-2-naphthoic acid)). CAS-number (octreotide pamoate): 135467-16-2.

  • N-terminally biotin-labeled Aβ40.

  • Melatonin

    Bachem

    Melatonin reverses the darkening effect (on skin) of melanotropin and inhibits LH-secretion. Shukla et al. observed that melatonin stimulates the nonamyloidogenic processing of APP via positive transcriptional regulation of ADAM10 and ADAM17 acting as α-secretases. Melatonin has been…

  • Glucagon sulfoxide shows the same maximal glucose mobilizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor.

  • This bombesin analog is a specific antagonist of the bombesin receptor.

  • The flexible LC spacer increases the accessibility of the biotin moiety.

  • Stable isotope-labeled orexin A analog for use as internal standard in a sensitive quantitative mass spectrometry assay of the peptide hormone in cerebrospinal fluid.

  • Anderson and Webb could verify using transmission electron microscopy that N-terminal labeling of Aβ40 with TAMRA and other fluorescent dyes does not prevent the formation of protofibrils and amyloid fibrils of various widths.

  • During heparin-induced self-aggregation of the four repeat domain peptides (R1–R4) excised from tau, R1, which resembles Tau Peptide (244-274), was the most resistive to filament formation. Its conformation remained unchanged. The peptide maintained the same random structure under both acidic…

  • Residue Lys87, contained in Tau Peptide (74-102) (Exon 3/Insert 2 Domain), is one of the glycation sites of PHF-tau in vitro.

  • Amyloid β-peptide (1-40) showed both neurotrophic and neurotoxic effects in dependence on the neuronal age and the concentration of the β-protein. Aβ 1-40 has been used as well as Aβ 1-42 to detect amyloid β-protein multimers in the cerebrospinal fluid of Alzheimer's…

  • Control peptide for LL37.

  • Two hepcidins have been found in mice, hepcidin-1, a homolog of human hepcidin-25 in serum and hepcidin-2, a pentacosapeptide with differing sequence in urine. Hepcidin-1 could be involved in murine brain iron metabolism.

  • H-7438 was obtained by dissolving Amyloid β-Protein (1-40) (H-1194) in HFIP, aliquoting, and removing the solvent as described in the literature.

  • Heavy isotope-labeled Glucagon useful for pharmacokinetic/pharmacodynamic studies in combination with Bachem product H-6790 Glucagon (1-29) (human, rat, porcine) or the corresponding generic API (Glucagon).

  • The flexible LC spacer increases the accessibility of the biotin moiety.

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