GenScript Life Science Reagents
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BDCA-2 is a novel type II C-type lectin, which shows 50.7% sequence identity at the amino acid level to its putative murine ortholog, the murine dendritic cell–associated C-type lectin 2. In addition to its antigen capturing function, BDCA-2 can mediate potent inhibition of induction of IFN-a/ß…
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SIRPa Fc Chimera, Human
GenScriptSignal regulatory protein alpha (SIRPa, designated CD172a), is also known as CD172 antigen-like family member A (CD172a), also called SHPS-1 (SHP substrate 1) and previously, MyD-1 (Myeloid/Dendritic-1), which is a monomeric about 90kDa type I transmembrane glycoprotein that belongs to the…
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LAH4,1mg
GenScriptThe a-helix of the amphipathic peptide antibiotic LAH4 (KKALLALALHHLAHLALHLALALKKA-NH2) strongly interacts with phospholipid membranes, demonstrating in vitro transfection efficiencies comparable to those of commercially available reagents.
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GenBuilder?? Plus Cloning Kit
GenScriptThe GenBuilder Plus Cloning Kit enables seamless and one-step cloning of multiple DNA fragments into a linearized vector. The proprietary enzyme mix fuses together DNA fragments efficiently and precisely by recognizing 15-40 bp overlaps at the end of each fragment. The system allows cloning of DNA…
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293/TP Stable Cell Line,2vials
GenScriptThe thromboxane A2 (TxA2) receptor (TP) is a member of the G protein-coupled receptor (GPCR) superfamily which mediates TxA2-induced platelet aggregation and vasoconstriction. Dysregulation of TxA2 synthesis and function has been implicated in the pathogenesis of a number of disease states…
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Rituximab (Rituxan) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the trea™ent of hematological cancers and autoimmune diseases. When Rituximab binds to CD20 on the surface of normal and malignant B cells, natural killer (NK) cells is…
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1321N1/P2Y6 Stable Cell Line,2vials
GenScriptP2Y receptors are one of three families of extracellular receptors for purine and pyrimidine nucleotides involved in purinergic signaling. In heterologous expression systems, recombinant P2Y1, P2Y2, P2Y4, P2Y6 receptors couple to G proteins (mainly Gq) which, in turn, activate…
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GenScript THE ™ c-Myc Antibody [HRP], mAb, Mouse is immunoaffinity purified from mice ascites with protein A and then conjugated to horseradish peroxidase. Mouse Anti-c-Myc [HRP] Monoclonal Antibody is suitable for detecting the expression level of c-Myc in fusion proteins.
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Streptavidin is a tetrameric protein purified from Streptomyces avidinii. It has wide use in numerous molecular biological protocols dues to its strong affinity for biotin. NWSHPQFEK (Strep II tag) is a nine amino acid peptide with high specificity and affinity towards streptavidin. GenScript THE…
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IL-22, Mouse
GenScriptInterleukin-22 (IL-22) is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequence, but differ in their biological function. IL-22 is produced by T lymphocytes, and…
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IGF-BP-3, Human
GenScriptIGF-BP3 is a 30 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals and it is also found in ª-granules of platelets. In addition to its ability to modulate the activity of IGF-I and IGF-II, IGF-BP3 exerts inhibitory effects on follicle…
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EGF, Human
GenScriptEpidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through the EGF receptor (EGFR) also known as erbB1,…
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MIG/CXCL9, Mouse
GenScriptChemokine (C-X-C motif) ligand 9 (CXCL9), also known as monokine induced by interferon gamma (MIG), is a small cytokine belonging to the CXC chemokine family. The CXCL9 gene is induced in macrophages and in primary glialcells of the central nervous systemin response to IFN?. CXCL9 has been shown…
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GenScript innovating Endotoxin-free pipette tips are designed for compatible use with most common pipetts from different manufacturers, which brings more flexibility. All tips are available in 1 version (1 ml) for laboratory routines. In addition, the tip can be used to dilute or aliquot sample…
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IL-19, Human
GenScriptHuman Interleukin 19 (IL-19) is a member of the IL-10 family of related cytokines. IL-19 expression has been observed in keratinocytes and monocytes. IL-19 binds a receptor complex consisting of IL-20R alpha and the IL-20 R beta. This receptor complex is also shared by IL-20 and IL-24.
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IL-2, Human
GenScriptInterleukin-2 (IL-2) is a Oglycosylated, four a-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, ?d T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and…
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IL-7, His, Mouse
GenScriptInterleukin-7 (IL-7), also known as lymphopoietin 1 and pre-B cell factor, is a hematopoietic growth factor belonging to the IL-7/IL-9 family. It is produced by keratinocytes, dendritic cells, hepatocytes, neurons and epithelial cells. IL-7 binds and signals through IL-7 receptor,a heterodimer…
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The ß-adrenergic receptors are linked to G proteins. The ß-receptor has three known subtypes. Beta-1 receptors primarily regulate myocardial tissue and affect the rate of contraction via impulse conduction. Beta-2 receptors regulate smooth muscle tone and influence vascular and bronchiolar…
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IL-4, Mouse
GenScriptInterleukin-4 (IL-4) is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression. It has important effects on the growth and differentiation of different immunologically competent cells. Interleukin-4 is produced by mast cells, T…
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PDGF-CC, Human
GenScriptPlatelet-Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle, connective tissue, bone and cartilage cells, and some blood cells. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic…
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GRO alpha/CXCL1, Human
GenScriptChemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO-a, KC, neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). Human GRO-a, GRO-ß (MIP2a),and GRO-? (MIP2ß)are…
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PD-1 Fc Chimera, Human
GenScriptProgrammed cell death protein 1 , also known as PD-1 and CD279 (cluster of differentiation 279) or PDCD1, is a protein that in humans is encoded by the PDCD1 gene. PD-1 is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells and pro-B cells.PD-1 binds…
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TPO, His, Human
GenScriptThrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets.…
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M-CSF, Human(CHO-expressed)
GenScriptHuman Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages. M-CSF is mainly produced by monocytes,…
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SUMO-tag Antibody(4G11E9), mAb, Mouse
GenScriptSUMO tags are emerging as a viable alternative for increasing both the expression and solubility of otherwise hard-to-express proteins. The SUMO tag can be cleanly excised using SUMO protease, which recognizes the conformation of SUMO protein rather than a specific sequence within SUMO. The SUMO…
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THE™ cAMP Antibody, mAb, Mouse
GenScriptAdenosine 3, 5-cyclic monophosphate (cyclic AMP; cAMP) is one of the most important intracellular secondary messengers for transduction events. cAMP is also involved in regulating neuronal, glandular, cardiovascular, immune, and other functions and actions. A number of hormones, such as ACTH, TSH,…
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Influenza A NP(366-374) Strain
GenScriptThis peptide is an H2-Db-restricted epitope from the Influenza A/PR/8/34 nucleoprotein.
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CHO-K1/NK3 Stable Cell Line,2vials
GenScriptTachykinins are peptides sharing a common C-terminal amino acid sequence: Phe-X-Gly-Leu-Met-NH2. This neuropeptide family is composed of substance P, neurokinin A, and neurokinin B, which are widely distributed in mammalian central and peripheral nervous systems. These three molecules…
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TNF-a, Mouse (P. pastoris-expressed)
GenScriptSharing 79% sequence identity with human Tumor Necrosis Factor-alpha (hTNF-a), mouse Tumor Necrosis Factor-alpha (mTNF-a) is a cytokine mainly expressed by immune cells [1] . A type II transmembrane protein, TNF-a is further proteolytically processed to a soluble form [2] . The trimeric active…
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dNTP (10 mM each) =99% HPLC
GenScript10 mM dNTP Mix is suitable for use in PCR, sequencing, nick translation, fill-ins, cDNA synthesis, TdT tailing reactions, and the dilution of radiolabeled dNTPs. These nucleotides are supplied as convenient, ready-to-use solutions in sterilized water. The 10 mM dNTP Mix contains all four…
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