Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) protein 9 system provides a robust and multiplexable genome editing tool, enabling researchers to precisely manipulate specific genomic elements, and facilitating the elucidation of target gene function in…

Interleukin-6 Receptor (IL-6R) is a single trans-membrane protein that is the receptor for Interleukin-6 (IL-6). IL-6R forms a hexameric complex upon binding 2 molecules of IL-6 and two molecules of glycoprotein 130 (gp130) which activates intracellular JAK/STAT pathways. Although the normal form…

Single donor specimens collected from donors prior to and continuing through disease progression.

The rabbit immune system generates antibody diversity and optimizes affinity. GenScript utilizes MonoRab™ technology to generate high affinity and specific monoclonal rabbit antibodies. The HA tag is composed of several amino acids containing YPYDVPDYA and does not appear to interfere with…

Evaluate the performance of nucleic acid tests for determination of the absence of EV nucleic acids Formulated with purified, intact organisms Organisms are chemically modified to render them noninfectious Refrigerator stable—store between 2 and 8°C Purified protein matrix…

Atezolizumab is a fully humanized, engineered monoclonal antibody of IgG1 isotype against the protein programmed cell death-ligand 1 (PD-L1). Atezolizumab blocks the interaction of PD-L1 with programmed cell death protein 1 (PD-1) and CD80 receptors (B7-1Rs). PD-L1 can be highly expressed on…

IL-16 is a CD8 + T cell-derived cytokine that induces chemotaxis of CD4 + T cells and CD4 + monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a…

Single donor specimens collected from donors prior to and continuing through disease progression.

Single donor specimens collected from donors prior to and continuing through disease progression.

Hypocretin (orexin) receptor 2, also known as OX2, is a human protein encoded by the HCRTR2 gene. Orexin A and orexin B are neuropeptides originally identified as endogenous ligands for OX2. Orexin neuropeptides are produced by a small group of neurons in the lateral hypothalamic and perifornical…

Evaluate the performance of nucleic acid tests for determination of the presence of vaginal bacterial and fungal nucleic acids Formulated with purified, intact organisms Organisms are chemically modified to render them noninfectious Refrigerator stable—store between 2 and 8°C Purified protein…

The ZymoBIOMICS Gut Microbiome Standard is an accurately quantified microbial community mimicking the human gut microbiome. The challenges it presents to microbiomics profiling allows researchers to validate protocols and fine-tune them for gut microbiome research and act as a positive control for…

The SeroDetect HCV-Ab Mixed Titer Panel I is intended for use with in vitro assay procedures for the determination of antibodies to Hepatitis C Antigen (Anti-HCV).

Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine that was previously called monocyte-specific chemokine 3 (MCP-3). Due to CCL7 possessing two adjacent N-terminal cysteine residues in its mature form, it is classified within the subfamily of chemokines known as CC chemokines. CCL7…

Nivolumab (Opdivo) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the trea™ent of patients with unresectable or metastatic melanoma. Nivolumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its…

The widespread neuropeptide vasoactive intestinal peptide (VIP) has two receptors VPAC1 and VPAC2. The vasoactive intestinal polypeptide receptor VPAC1 is G_s-coupled GPCRs expressed in the lung, prostate, peripheral blood leukocytes, liver, brain, small intestine colon, heart, spleen,…

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. It is a dimer of alpha (α) and beta (β) chains. β-tubulin is ubiquitously expressed with highest levels…

ANXA5 , also known as annexin V , is a member of the annexin family of calcium-dependent phospholipid binding proteins which are involved in membrane-related activity along exocytotic and endocytotic pathways. ANXA5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel…

QuickAmp qPCR kits have been developed for fast qPCR and are designed for superior sensitivity and specificity with probe-detection technology, including TaqMan®, molecular beacon, and Scorpions® probes. A combination of the latest advances in buffer chemistry and PCR enhancers, in…

Programmed cell death 1 ligand 1 is one of the two ligands of PD-1. PD-L1 is expressed on macrophages, T cells, B cells, NK cells, DCs and some cancer cell surface. Binding of PD-1 with PD-L1 could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus,…

Wedge is used for holding precast gel in place.

An analytical reference standard that is structurally similar to known phytocannabinoids; intended for research and forensic applications

Human secretin stimulates the secretion of bicarbonate by the pancreas and inhibits the production of gastrin and acid production in the stomach. Human secretin also potentiates the release of digestive enzymes from the pancreas triggered by cholecystokinin.

Evaluation Panels may be used to evaluate assay characteristics, confirm performance claims and ultimately ensure the assay is fit for purpose. The Hepatitis C Evaluation Panel comprises two genotypes at high, medium and low levels.

The Scepter 3.0 handheld automated cell counter provides a fast and convenient method for counting cells and particles and is compatible with both the Scepter 3.0 40 and 60uM sensors. The system employs the Coulter principle in a miniaturized, handheld, format enabling rapid cell counting; what…

Interleukin-1 Beta (IL-1ß) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These…

Cytotoxic T lymphocyte-associated molecule-4 (CTLA-4) is a cell surface molecule that is closely related to CD28, and a powerful negative regulator of T cell activation. Structurally, CTLA-4 is a member of the Ig superfamily, having a single extracellular V-like domain , homology with CD28; The…

Molecular Q panels consist of four individual levels, including a negative and are intended to evaluate an assay's clinical range.This dedicated Molecular Q Panel is designed to monitor the performance of molecular assays used in the detection of Chlamydia trachomatis and Neisseria gonorrhoea…

Signal regulatory protein alpha (SIRPa, designated CD172a), is also known as CD172 antigen-like family member A (CD172a), also called SHPS-1 (SHP substrate 1) and previously, MyD-1 (Myeloid/Dendritic-1), which is a monomeric about 90kDa type I transmembrane glycoprotein that belongs to the…

Bevacizumab (Avastin) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the trea™ent of patients with colon cancer, lung cancer, glioblastoma, renal-cell carcinoma, and age-related macular degeneration. As angiogenesis inhibitor, Bevacizumab…

Growth Hormone (GH), mouse is a member of the somatotropin / prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional…

Analytical Q panels are intended for use in the validation and verification of molecular diagnostic assays, helping to establish the LOD and ensuring the assay is linear throughtout the dynamic range. This dedicated Analytical Q Panel is designed to monitor the performance of molecular assays used…