Aprotinin is a monomeric globular protein which inhibits several serine proteases including trypsin, chymotrypsin, plasmin and kallikrein. Furthermore, its action on kallikrein leads to inhibition of formation of factorXIIa. The binding of aprotinin to proteases is reversible with dissociation of…

Enzymes regularly used in laboratory applications often require preparation of fresh solution before each use. Making fresh enzyme solution for each application is time consuming and wasteful. A wide variety of enzyme preparations in a ready-to-use format are offered. LongLife™ enzyme…

(4’-demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside], 4’ -(dihydrogen phosphate)) An inhibitor of topoisomerase II. Supplied as 50μl 100mM solution.

Taq Plus DNA Polymerase is a mixture of Taq DNA Polymerase and Pfu, a proofreading DNA Polymerase, which allows for the amplification of long templates, up to 20kb, with high fidelity. The two enzymes act synergistically during PCR to generate more accurate and longer PCR products with greater…

Features Specificity: Inhibits serine, plasmin, porcine kallikrein and cysteine proteases, including papain and cathepsin B. Does not inhibit chymotrypsin and thrombin. Molecular weight: 475.59 Purity: Three tautomeric isomers in solution Solubility: Soluble in H₂O…

E-64 L-trans-epoxysuccinyl-leucylamide-(4-guanido)-butane or N-[N-(L-trans-carboxyoxiran-2-carbonyl)-L-leucyl]-agmatine Features CAS Number: 66701-25-5 Molecular Formula : …

SG-Carboxypeptidase B (Recombinant)™is the rat carboxypeptidase B expressed in E. coli. Carboxypeptidase B specifically hydrolyses basic amino acids including lysine, arginine and histidine from the C-terminal end of polypeptides. It is used in sequencing protein and peptides. Other…

Isovaleryl-Val-Val-AHMHA-Ala-AHMHA where AHMHA= (3S, 4S)-4-amino-3-hydroxy-6-methyl-heptanoic acid Specificity: A potent inhibitor of various aspartic proteases, including cathepsin D, renin, pepsin, bacterial aspartic proteases and HIV proteases. Solubility: Soluble in DMSO or methanol …

Features Synonyms: α-Toluenesulfonyl fluoride, Benzylsulfonyl fluoride, Phenylmethylsulfonyl fluoride CAS Number: 329-98-6 Molecular Formula: C₇H₇FOâ‚‚S Molecular Weight: 174.19 g/mol Activity: >99.9% …

SG -Arginine-C ™ endopeptidase (Clostripain, from C. histolyticum ) specifically hydrolyzes the carboxy peptide bond of Arginine. SG -Arginine-C ™ has been modified chemically by a propriety process to render the enzyme resistant to autolysis and stabilize enzymatic activity. In…

Enzymes regularly used in laboratory applications often require preparation of fresh solution before each use. Making fresh enzyme solution for each application is time consuming and wasteful. A wide variety of enzyme preparations in a ready-to-use format are offered. LongLife™ enzyme…

N-[(S)-1-carboxy-isopentyl)-carbamoyl-alpha-(2-iminohexahydro-4(S)-pyrimidyl]-L-glycyl-L-phenylalaninal Specificity: Inhibits serine proteases having a chymotrypsin-like specificity, including α, β γ, and δ chymotrypsin, and most cysteine proteases including cathepsins…

[(S)-1-Carboxy-2-Phenyl]-carbamoyl-Arg-Val-arginal Specificity: Inhibits Ca 2+ -dependent endopeptidases, including papain, trypsin-like serine proteases, some cysteine proteases and to a lesser extent plasmin. Higher specificity for trypsin and papain compared to leupeptin. Solubility: …

Pfu DNA Polymerase Mastermix [2X] is a premixed, ready-to-use solution containing Pfu DNA Polymerase, dNTPs, MgSO₄ and Reaction Buffer at optimal concentrations for efficient amplification of DNA templates by PCR. To prepare the final PCR, only primers and template DNA are added. Pfu Mix…

4-ethyl-4-hydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b] quinoline-3,14-(4H,12H)-dione A cytotoxic quinoline alkaloid that inhibits the DNA enzyme topoisomerase I (Topo I). Supplied as 1ml 2mM Features Synonym: CPT CAS Number: 7689-03-4 Linear Formula: …

Adenosylhomocysteine nucleosidase (EC 3.2.2.9) converts S-adenosylhomocysteine (AdoHcy) to S-(deoxy-D-ribos-5-yl)-L-homocysteine + adenine. A highly purified recombinant enzyme protein supplied at a 10µM concentration.

Calpain inhibitor I; N-[N-(N-Acetyl-L-leucyl)-L-leucyl]-L-norleucine Specificity: Cell permeable peptide aldehyde inhibitor of calpain I and to a lesser extent calpain II. Also inhibits other neutral cysteine proteases, cathepsin B and L and the proteasome. Solubility: Soluble in DMSO or…

A broad range, 100X concentrated, ready-to-use protease inhibitor cocktail. Bacterial ProteaseArrest ™ inhibits bacterial serine, cysteine and other bacterial specific proteases including aminopeptidases and aspartic proteases. An optional EDTA solution is provided for enhanced…

N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine hydrochloride Specificity: Competitive inhibitor of surface aminopeptidases, including aminopeptidase B (K_i=2nM), leucine aminopeptidase (K_i=20nM). Also inhibits aminopeptidases N; does not inhibit endoproteases. …

Trypsin is a serine protease that cleaves peptides on C-terminal end of lysine and arginine amino acid residues. The pH optimum of trypsin is pH 7.0-8.0. Trypsin is inhibited by serine protease inhibitors including TLCK (N-p-tosyl-L-lysine chloromethyl ketone), PMSF (phenylmethanesulfonyl…

A broad range, 100X concentrated, ready-to-use protease inhibitor cocktail. Mammalian ProteaseArrest™ inhibits mammalian serine, cysteine and other mammalian specific proteases including aminopeptidases, trypsin-like and aspartic proteases. An optional EDTA solution is provided for…

A class of polypeptide antibiotics isolated from the Steptomyces soil bacteria. Actinomycin D inhibits transcription by binding to DNA at the transcription initiation complex and therefore preventing elongation by the RNA polymerase. Supplied as 50μl 10mM solution. Features …

Enterokinase (Recombinant) is highly purified recombinant bovine enterokinase obtained from E. Coli. Enterokinase is highly specific serine protease that hydrolysis peptide bond at the carboxyl side of lysine residue preceded by four aspartic acids (FLAG-tag). Enterokinase is used for removal…

((8S,10S)-10-(4-amino-5-hydroxy-6-methyl-tetrahydro-2H-pyran-2-yloxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione) Doxorubicin (or hydroxyldaunorubicin) is an anthracycline antibiotic that intercalates DNA, inhibiting the unwinding of DNA by…

Enzymes regularly used in laboratory applications often require preparation of fresh solution before each use. Making fresh enzyme solution for each application is time consuming and wasteful. A wide variety of enzyme preparations in a ready-to-use format are offered. LongLife™ enzyme…

SG -Chymotrypsin ™ is a serine endopeptidase, which predominantly cleaves peptide bonds on the carboxy side of tyrosine, phenylalanine and tryptophan. In addition, chymotrypsin has a low catalytic activity against the carboxy side of leucine, methionine, alanine, aspartic and glutamic acids.…

SG -Lysine-C ™ endopeptidase, from Lysobacter enzymogenes , is a serine protease highly specific in cleaving peptide bonds at the carboxy side of lysine. Highly purified preparations of SG -Lysine-C ™ are chemically modified making the enzyme resistant to autolysis and stabilizing…