Solid Phase Extraction (SPE) Columns

Solid Phase Extraction (SPE) columns are essential tools in sample preparation, widely used for isolating analytes from complex matrices. These columns facilitate efficient purification, making them indispensable in various fields, including environmental testing, pharmaceuticals, and food safety.

SPE columns with high-quality sorbent materials to ensure precise separation and consistent results. Advanced features include a wide range of sorbent chemistries, catering to different application needs, and robust construction that prevents channeling and ensures uniform flow rates.

The practical benefits of these features are clear: improved accuracy in analyte detection, reduced sample preparation time, and minimized solvent usage. SPE columns streamline workflows, providing reliable and reproducible outcomes.

Available in various sizes and formats, including standard SPE tubes, these columns offer flexibility to match specific sample volumes and requirements. Whether you need small-scale extractions or larger batch processes, there is an SPE column to meet your needs.

For added convenience, many SPE columns are compatible with automated systems and come with accessories like adaptors and collection plates, ensuring seamless integration into your laboratory setup.



We also provide lab chromatography columns at Thomas Sci.

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  • Sep-Pak Accell Plus QMA Carbonate Plus Light cartridges contain a silica-based, hydrophilic, strong anion-exchanger with a large pore size (300Å) and a carbonate counter-ion. These cartridges are used for extraction of anionic analytes in aqueous and non-aqueous solutions when the chloride…

  • Avantor - J.T.Baker®

    Adapter (8330D64) 10 ea. Adaptors for 15, 75-ml Reservoirs & 1,3,6 m 1 'Baker' spe™ Columns

  • Caplugs Evergreen®

    Mini columns are molded in polypropylene for molecular biology studies. Columns feature a HDPE filter of medium porosity (45-90 micron).  16 mm x 38.3 mm dimensions

  • MACHEREY-NAGEL

    Features More than 50 different sationary phases available e.g., silica gel based: unmodified, C8, C18, NH2, CN; Polyermic material: HR-X, HLB, PA; mixed-mode, special combinations, aluminum oxide, kieselguhr (XTR) etc. NP, RP, ion exchanger and for special applications Different…

  • MACHEREY-NAGEL

    Polystyrene-divinylbenzene adsorbent resin for SPE Features Highly porous polystyrene-divinylbenzene copolymer specific surface 1200 m2/g, particle size 50–100 μm very high binding capacity, up to 30 % of adsorbent weight (for comparison: silica adsorbents about 3 %) …

  • MilliporeSigma

    Dispersive SPE (dSPE), often referred to as the "QuEChERS" method (Quick, Easy, Cheap, Effective, Rugged, and Safe), is modern sample prep technique that is becoming increasingly popular in the area of multi-residue pesticide analysis in food and agricultural products. Using the QuEChERS method,…

  • MACHEREY-NAGEL

    Weakly basic secondary and tertiary ammonium polymeric anion exchanger for SPE Features Base material spherical PS/DVB copolymer, pore size 55–65 Å, particle sizes 45 µm or 85 µm (standard) very large specific surface 850 m2/g, pore volume 1.2–1.4 cm3/g, pH…

  • MACHEREY-NAGEL

    Magnesium silicate for SPE Features Matrix magnesium silicate (MgO – SiOH 15:85), high purity, particle size 150–250 µm Recommended application: organic tin compounds, aliphatic carboxylic acids, PCBs, PAHs

  • Ideal for Flash separations from 10 mg up to 300 g Features For convenient operation and reliable upscaling the complete program of ready-to-use Flash cartridges for the Isco Companion® and other Teledyne Isco CombiFlash® systems, or as stand-alone version for all…

  • Ideal for Flash separations from 10 mg up to 33 g Features For convenient operation and reliable upscaling the complete program of ready-to-use Flash cartridges for the Isco Companion® and other Teledyne Isco CombiFlash® systems, or as stand-alone version for all…

  • Populate base plate with only the wells needed 50 µL elution volume for minimal sample dilution and reduced evaporation time Optimized well geometry for 5 and 10 mg sorbent masses Use with vacuum or positive pressure The internal diameter, frit design, and sorbent material of…

  • Affinimip SPE is a selective solid phase extraction based upon molecularly printed polymers (MIP). It combines the advantages of Immune-affinity columns in terms of selectivity and a classic solid phase extraction (SPE) in terms of robustness and costs. This selectivity and robustness combines to…

  • MACHEREY-NAGEL

    Special products for determination of pesticides in food samples QuEChERS method and pre-mixes Within a few years after its development by Anastassiades et al. the QuEChERS method has gained a leading position for the determination of pesticide residues in food samples by GC-MS or LC-MS,…

  • MACHEREY-NAGEL

    Features More than 50 different sationary phases available e.g., silica gel based: unmodified, C8, C18, NH2, CN; Polyermic material: HR-X, HLB, PA; mixed-mode, special combinations, aluminum oxide, kieselguhr (XTR) etc. NP, RP, ion exchanger and for special applications Different…

  • Reservoir columns for application of medium-size samples.

  • Mixed-mode strong cation exchange columns for basic analyte extraction High surface area and capacity ensure highly reliable retention characteristics No secondary interactions from silanol groups for accurate results Higher sample loading due to high surface area Recover clean…

  • Reversed Phase (Non-Polar) 25% carbon loading Silica-based particles reduce pressure drop and increase flow reproducibility Average particle size of 45 µm and pore diameter of 60 Angstrom to reduce pressure drop and increase flow reproducibility Agilent’s…

  • For individual packing of SPE columns with CHROMABOND® adsorbents.

  • quick-ship

    MACHEREY-NAGEL

    Features More than 50 different sationary phases available e.g., silica gel based: unmodified, C8, C18, NH2, CN; Polyermic material: HR-X, HLB, PA; mixed-mode, special combinations, aluminum oxide, kieselguhr (XTR) etc. NP, RP, ion exchanger and for special applications Different…

  • MilliporeSigma

    Dispersive SPE (dSPE), often referred to as the "QuEChERS" method (Quick, Easy, Cheap, Effective, Rugged, and Safe), is modern sample prep technique that is becoming increasingly popular in the area of multi-residue pesticide analysis in food and agricultural products. Using the QuEChERS method,…

  • Retention Mechanism: Normal phase or Anion-exchangeSample Matrix Compatibility: Organic or aqueous solutions •Polymerically bonded, aminopropyl phase that is very polar in nature (hydrogen bonding) allowing for both normal phase and ion exchange applications •A weak anion exchanger with a pKa of…

  • MACHEREY-NAGEL

    Features More than 50 different sationary phases available e.g., silica gel based: unmodified, C8, C18, NH2, CN; Polyermic material: HR-X, HLB, PA; mixed-mode, special combinations, aluminum oxide, kieselguhr (XTR) etc. NP, RP, ion exchanger and for special applications Different…

  • Legal Information: Supelclean is a trademark of Sigma-Aldrich Co. LLC

  • Empty SPE Tubes allow you to pack your own SPE cartridges Synonyms: pk 20, Empty Fritted 20-ml SPE Tubes

  • Affinimip SPE is a selective solid phase extraction based upon molecularly printed polymers (MIP). It combines the advantages of Immune-affinity columns in terms of selectivity and a classic solid phase extraction (SPE) in terms of robustness and costs. This selectivity and robustness combines to…

  • MACHEREY-NAGEL

    Hydrophilic-lipophilic balanced N-vinylpyrrolidone-divinylbenzene resin for SPE Features Hydrophilic-lipophilic balanced N-vinylpyrrolidone-divinylbenzene copolymer pH stability 1–14 Spherical particles 30 μm or 60 μm (standard) Pore size 65 Å Specific surface…

  • MACHEREY-NAGEL

    Polar, bifunctionally modified polystyrene-divinylbenzene copolymer Features Polar modified polystyrene-divinylbenzene copolymer with a weak anion exchanger, specific surface 650–700 m2/g, particle size 80 µm, pore size 50 Å, pH stability 1–14 The Easy…

  • MACHEREY-NAGEL

    Special silica phase for SPE of THC and derivatives acidic analytes from biological fluids (urine, blood ...) Features Base material silica, pore size 60 Å, particle size 45 µm, specific surface 500 m2/g, pH stability 2–8 special bifunctional modification – C8 /…

  • Agilent Technologies

    Ensures fast, reliable extraction of anionic compounds Inert to a wide variety of solvents Stable for pH ranges 0 - 14 Water-wettable The Agilent SampliQ Strong Anion Exchange (SAX) polymeric resin is a mixed-mode, tertiary amine-modified divinyl benzene polymer that…

  • Ideal for Flash separations from 10 mg up to 300 g Features For convenient operation and reliable upscaling the complete program of ready-to-use Flash cartridges for the Isco Companion® and other Teledyne Isco CombiFlash® systems, or as stand-alone version for all…

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