Separation Methods Technologies HPLC Columns

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  • Separation Methods Technologies

    SMT CIB-IgG are silica-based packing materials designed for for both high performance and low-pressure purification of protein A. In production of the IgG affinity-type columns, SMT utilizes its proprietary technique of self-assembled monolayer (SAM) of bonding to first immobilize unique mixed…

  • Separation Methods Technologies

    Elite-C18 Series: SMT SAM-C18 phases with the intermediate functional ligand coverage confirmed with carbon analysis results of 16% carbon load. In these series, the density of the functional ligand, octadecyl molecule or C18, is moderated with the proprietary spacer molecule to ensure maximum…

  • Separation Methods Technologies

    SMT manufactures ultra-stable cyanopropyl [CN] columns for normal and reversed-phase chromatographic separation modes. These columns have some special characteristics. When used in normal phase mode, with relatively nonpolar solvents, CN-stationary phase can separate many polar compounds just like…

  • Separation Methods Technologies

    OL Series SMT SAM-C8 phase with the lowest functional ligand coverage confirmed with carbon analysis results of 6% carbon load. In these series, the proportional ratio of the functional ligand, octyl or C8 molecule , mixed with the proprietary spacer molecule, is reduced. The result is a…

  • Separation Methods Technologies

    SMT-Phenyl column provides unique selectivity for aromatic compounds when compared to other reversed-phase packings such as C18 and C8. The pie electrons of the phenyl group can interact with the aromatic ring of an analyte to increase retention relative to less or non-aromatic analytes. Unique…

  • Separation Methods Technologies

    SMT-Phenyl column provides unique selectivity for aromatic compounds when compared to other reversed-phase packings such as C18 and C8. The pie electrons of the phenyl group can interact with the aromatic ring of an analyte to increase retention relative to less or non-aromatic analytes. Unique…

  • Separation Methods Technologies

    SMT AquSep is unique reversed phase packing material designed to have both hydrophobic and truly hydrophilic spacer ligands. The mixed-phase consists of a meticulously controlled mixture of hydrophobic, C18 molecules, and proprietary hydrophilic molecules, chemically attached on the silica…

  • Separation Methods Technologies

    SMT-C6F5 columns consist of Pentafluorophenyl as the functional ligand. The columns offer selectivities that are different from other reversed-phase columns when applied to separation of halogenated compounds, ketones, esters, and taxols. Taxol has been approved by the US Food and Drug…

  • Separation Methods Technologies

    SMT-TNT columns are specially designed C18 column for use in the reversed-phase separation of nitroaromatic and nitroamine derivatives. The isomeric nature of these explosive compounds is the reason for the difficulty in their separation. The standard test method for the analysis of seven…

  • Separation Methods Technologies

    SMT Phenyl bulk packings provides unique selectivity for aromatic compounds when compared to other reversed-phase packings such as C18 and C8. The ìÛ-electrons of the phenyl group can interact with the aromatic ring of an analyte to increase retention relative to less or non-aromatic…

  • Separation Methods Technologies

    SMT Phenyl bulk packings provides unique selectivity for aromatic compounds when compared to other reversed-phase packings such as C18 and C8. The ìÛ-electrons of the phenyl group can interact with the aromatic ring of an analyte to increase retention relative to less or non-aromatic…

  • Separation Methods Technologies

    SMT CIB-ProteinA are silica-based packing materials de- signed for both high performance and low-pressure purification of antibodies, IgG. In production of the ProteinA affinity-type columns, SMT utilizes its proprietary technique of self-assembled monolayer (SAM) of bonding to first immobilize…

  • Separation Methods Technologies

    SMT Phenyl-Hexyl column or PhenH column, like the other SMT Phenyl columns, provides unique selectivity for aro- matic compounds when compared to other reversed-phase packings such as C18 and C8. The ìÛ-electrons of the phe- nyl group can interact with the aromatic ring of an analyte…

  • Separation Methods Technologies

    SMT SAM-C6 columns consist of Hexyl as the functional ligand. The columns offer selectivities that are different from C8 and C18 reversed-phase columns when applied to separation of polyaromatic hydrocarbons. SMT-C6 columns are specially designed as complementary alternatives for the separation…

  • Separation Methods Technologies

    When silica is used as the stationary phase, the functional groups involved in separation are the surface silanols. However, metal impurities in silica may provide additional sites of interaction for solutes of interest. SMT uses high purity silica packing materials that are available in variety of…

  • Separation Methods Technologies

    SMT manufactures bulk packings with short carbon chains for rapid analysis of basic, neutral, and mildly acidic drugs and small molecules. These columns provide excellent baseline resolution for small basic molecules including therapeutic drugs. The bonding scheme ensures proper deactivation of the…

  • Separation Methods Technologies

    ODL Series: SMT SAM-C18 phase with the lowest functional ligand coverage confirmed with carbon analysis results of 12% carbon load. In these series, the proportional ratio of the functional C18 molecule, mixed with the proprietary spacer molecule, is reduced. The result is a packing material with…

  • Separation Methods Technologies

    SMT-Diol bulk packings are developed as an alternative for silica bulk packings used in separation methods. The Diol [-OH] functional group is controlled, and as such, provides more reproducible separation when compared to separation on silanols [-OH] from bare silica surface. Furthermore, the…

  • Separation Methods Technologies

    SMT manufactures the first series of commercially available silica based CIB-Ovomucoid columns for high performance chiral separation of acid, base and neutral molecules. This total coverage technology ensures complete elimination of non-specific binding sites on the silica surface. The rigidity of…

  • Separation Methods Technologies

    Chiral compounds, or enantiomers have identical molecular structures that are related as mirror images of one another much like a left hand is related to a right hand. Rapid and accurate stereochemical resolution of enantiomeric molecules has become a challenge in various aspects of pharmaceuticals…

  • Separation Methods Technologies

    SMT-Diol columns are developed as an alternative for silica columns used in normal phase separation methods. The Diol [-OH] functional group is controlled, and as such, provides more reproducible separation when compared to separation on silanols [-OH] from bare silica surface. Furthermore, the…

  • Separation Methods Technologies

    SMT MetalSep is offered as bulk packing materials for low pressure liquid chromatography, solid phase extraction, preparatory and process scale applications. The packings consist of proprietary strong cation exchange functional ligands that are chemically attached on silica substrate using SAM…

  • Separation Methods Technologies

    SMT-C30 columns consist of Triacontyl as the functional ligand. The columns offer selectivities that are much different from C18 reversed-phase columns when applied to separation of carotenoid and related compounds. Carotenoids consist of very diverse groups of molecules that include nonpolar…

  • Separation Methods Technologies

    SMT SCX Bulk Packings are silica-based Strong Cation eXchange packing materials developed for separation of cationic compounds. SMT SCX Bulk Packings consist of chemically attached hydrophilic surface derivatized to form sulfonic acid functionality. The technique of SAM is used in the bonding…

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