Biologically Active Small Molecules

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MP Biomedicals Biologically Active Small Molecules

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  • n-Propyl Gallate

    MP Biomedicals

    n-Propyl gallate is an ester formed by the condensation of gallic acid and propanol. This antioxidant has been added to foods containing oils and fats to prevent oxidation. n-Propyl gallate is used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes…

  • Calyculin A from Discodermia calyx (Marine Sponge)

    MP Biomedicals

    Calyculin A has IC50 values of approximately 1 nm for both PP1 and PP2A. More than 10 times more effective for PP1 than okadaic acid. Calyculin A is a Phosphatase inhibitor with very potent inhibitory activity against both PP1 and PP2A phosphatases. It is a Potent tumor promoter. …

  • Methotrexate, USP and EP Grade

    MP Biomedicals

    Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of…

  • Lecithin from Egg

    MP Biomedicals

    Lecithin is the major membrane phospholipid in eukaryotic cells. In addition to being the major structural component of cellular membranes, it serves as a reservoir for several lipid messengers. It is the source of the bioactive lipids lysophosphatidylcholine, phosphatidic acid, diacylglycerol,…

  • Spermine Tetrahydrochloride

    MP Biomedicals

    Spermine is a naturally occuring polyamine that occurs in all eukaryotes, but is rare in prokaryotes. It is essential for cell growth in both normal and neoplastic tissue. Spermine is formed through the addition of an aminopropyl group to spermidine by spermine synthase. Spermine is strongly basic…

  • Cholesterol

    MP Biomedicals

    Cholesterol is the principal sterol of the higher animals, found in all body tissues. It is the main constituent of gallstones and all biological membranes. Approximately 25% of total brain lipid is cholesterol. Cholesterol, followed by the chemical suffix -ol for an alcohol, is an organic chemical…

  • Bilirubin from Porcine Gall Bladder

    MP Biomedicals

    Bilirubin is the principal pigment of bile and constituent of many biliary calculi and also found in blood. As the major end-product of the biological breakdown of heme, bilirubin is the chromophore responsible for coloration in various forms of jaundice. Bilirubin is suitable for use in the…

  • Caffeine, Anhydrous

    MP Biomedicals

    Caffeine is a well-known drug commonly used as a mild stimulant, found in dietary sources such as coffee, tea, and cocoa. A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine…

  • Thymidine

    MP Biomedicals

    Thymidine is a nucleoside composed of deoxyribose (a pentose sugar) joined to the pyrimidine base thymine. Deoxythymidine can be phosphorylated with one, two or three phosphoric acid groups, creating respectively dTMP, dTDP or dTTP (deoxythymidine mono- di- or triphosphate.) It exists in solid form…

  • Norethindrone

    MP Biomedicals

    Norethindrone is a synthetic progestin that possesses antiestrogenic effects, where in low doses it is progestational and in high doses it is antiestrogenic. It also causes a time-dependent loss of cytochrome P-450 when incubated in vitro with rat liver microsomal fractions and NADPH-generating…

  • Nicotine Bitartrate Dihydrate

    MP Biomedicals

    Nicotinic acetylcholine receptor agonist isolated from Nicotiana tabacum and Nicotiana rustica. Nicotine Tartrate finds an application as the nicotine active in a wide range of smoking cessation products such as nicotine lozenges and nicotine sub-lingual tablets. (-)-Nicotine ditartrate is a…

  • Concanavalin A from Canavalia ensiformis seeds (jack beans)

    MP Biomedicals

    Pure Canavalia ensiformis lectin (Con A) from Jackbean. Isolated by affinity chromatography on cross-linked dextran. Con A exists as a dimer below pH 5.0 and and at pH >7 it exists as a tetramer. Con-A is not a glycoprotein. The monomeric molecular weight of Con-A is 25,500. Con-A does not…

  • DL-Epinephrine

    MP Biomedicals

    (+/-)-Epinephrine is also known as adrenaline and is a hormone as well as a neurotransmitter that is part of a group of monoamines called catecholamines. It is used medically to treat a number of cardiac and respiratory conditions as well as serving as a local anesthetic. …

  • Cholesterol

    MP Biomedicals

    Cholesterol is the principal sterol of the higher animals, found in all body tissues. It is the main constituent of gallstones and all biological membranes. Approximately 25% of total brain lipid is cholesterol. Cholesterol is suitable for use in liposome preparations.

  • Dithranol

    MP Biomedicals

    Dithranol (1, 8 - dihydroxy-9-anthrone) is also called as anthralin. It is a vital topical antipsoriatic drugs. Dithranol, an athracene derivative, is a free radical generating mitochondrial poison that induces apoptosis in keratinocytes. Dithranol may be used as a matrix for matrix assisted…

  • Aprotinin from Bovine Lung

    MP Biomedicals

    Aprotinin is a single chain polypeptide (58 amino-acids) crosslinked by three disulfide bridges, showing competitive and reversible inhibiton of proteolytic and esterolytic activity. Aprotinin forms stable complexes with, and blocks the active sites of serine protease enzymes. It is found in bovine…

  • Sodium Valproate

    MP Biomedicals

    Valproic Acid, Sodium Salt is a branched chain fatty acid which is reported to enhance central GABAergic neurotransmission and inhibit Na+ channels. Sodium Valproate is reported to cause inositol depletion, activate the ERK pathway, inhibit GSK-3α and GSK-3β. Valproic Acid has been…

  • Hydrocortisone

    MP Biomedicals

    Hydrocortisone, a primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency. Hydrocortisone, known more formally as cortisone (INN, USAN, BAN), is a steroid hormone, produced by the zona…

  • D-myo-Inositol

    MP Biomedicals

    A lipotropic agent. D-myo-Inositol is a component of membrane phospholipids, glycosylphophatidylinositol anchors that bind glycoproteins to cell membranes, and inositol phosphate second messengers. It is a growth factor for animals as well as microorganisms. Myo-Inositol is the most abundant…

  • Arachidonic Acid

    MP Biomedicals

    Arachidonic acid is an essential fatty acid, and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. It occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and is a constituent of animal phosphatides. …

  • 5-Hydroxytryptamine Hydrochloride

    MP Biomedicals

    5-Hydroxytryptamine Hydrochloride is a neurotransmitter.

  • Deltamethrin

    MP Biomedicals

    This is a Type II pyrethrin and a potent inhibitor of calcineurin (protein phosphatase 2B). More recent study disputes its effectiveness as a calcineurin inhibitor. May also have varied effects on ion channels. Deltamethrin is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor…

  • Melatonin

    MP Biomedicals

    Melatonin is a hormone of the pineal gland. Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell…

  • Methotrexate

    MP Biomedicals

    Folic Acid antagonist; structurally similar to folic acid. Methotrexate is a mixture of 4-amino-10-methylfolic acid and closely related compounds. A potent anticancer agent. Blocks DNA synthesis by blocking the production of tetrahydrofolate cofactors required for the synthesis of thymidine.…

  • Hydrocortisone-21-Acetate

    MP Biomedicals

    Hydrocortisone 21 acetate is a drug which inhibits or suppresses most inflammatory responses of an allergic, bacterial, traumatic or anaphylactic origin, as well as being immunosuppressant. They include the corticosteroids (e.g. betamethasone, dexamethasone, fluorometholone, hydrocortisone acetate,…

  • Hydroxyurea

    MP Biomedicals

    Hydroxyurea is a inhibitor of DNA synthesis in vivo, and an antiviral and antineoplastic agent which is S-phase specific. A ribonucleotide reductase inhibitor - inhibits by forming a free radical nitroxide that binds a tyrosyl free radical in the active site of the enzyme. Induces fetal hemoglobin…

  • D-myo-Inositol

    MP Biomedicals

    D-myo-Inositol is a growth factor for animals as well as microorganisms. Myo-Inositol is the most abundant form of polyols that serves as a structural element of secondary messengers in eukaryotic cells. Inositol or cyclohexane-1,2,3,4,5,6-hexol is a chemical compound, a sixfold alcohol (polyol) of…

  • Atrial Natriuretic Peptide, Fragment 3-28

    MP Biomedicals

    Amino Acid Sequence: Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr [Disulfide bridge: 7-23]. Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts…

  • ß-Estradiol

    MP Biomedicals

    β-estradiol is a potent mammalian estrogenic hormone produced by the ovary. Triggers the production of gonadotropins leading to ovulation. β-Estradiol is used to study cell differentiation and transformations (tumorigenicity). The pharmacology and HPLC determination of β-Estradiol…

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