Antibiotics, Antimycotics & Preservatives, 100 mg
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Cefsulodin Sodium Salt
MP BiomedicalsCefsulodin is a third generation cephalosporin antibiotic that has very specific activity against Pseudomonas aeruginosa. It has no significant activity against other Gram-negative bacteria and very limited activity against Gram-positive bacteria and anaerobic bacteria. Cefuslodin is most…
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Nourseothricin Sulfate
G-BiosciencesNourseothricin Sulfate Streptothricin Sulfate, NTC, clonNAT MOLECULAR BIOLOGY GRADE Norseothricin contains both Streptothricin D (C31H58N12O10) and Streptothricin F (C19H34N8O8) components. …
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Tamoxifen
MP BiomedicalsTamoxifen is a Protein Kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in…
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Puromycin Dihydrochloride
G-BiosciencesMW: 544.43 C22H29N7O5 · 2HCl Mode of action and Anti-microbial spectrum: Puromycin is a protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3′-terminal end of aminoacyl-tRNA. It prevents…
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Dexamethasone
MP BiomedicalsDexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S…
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Valinomycin
MP BiomedicalsA metabolite with a broad antibiotic spectrum. Inhibitor of mitochonclrial action. K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes…
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Ascomycin
bioWORLDSynonyms: Immunomycin, FK520, FR-900520 Ascomycin is a macrolide immunosuppressant antibiotic. It is an ethyl analog of FK506. Ascomycin binds to the FK-506-binding protein FKBP12 and blocks the peptidyl-prolyl cis-trans isomerase activity of the protein. This bound complex inhibits…
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Puromycin Dihydrochloride
MP BiomedicalsPuromycin is an antibiotic of unique structure and biological activity. It is produced by fermentation using Streptomyces albo-niger. There are four aspects of puromycin's biological activity that are 1) antitumor effect; 2) nephrotoxic action; 3) inhibition of purine and/or protein synthesis…
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Tamoxifen Citrate Salt
MP BiomedicalsProtein Kinase C inhibitor. Tamoxifen Citrate Salt is a nonsteroidal triphenylethylene derivative. Tamoxifen and its metabolite 4-hydroxytamoxifen are mixed estrogen agonists/antagonists. Tamoxifen has been shown to protect bone from estrogen-deficiency bone loss and lower plasma cholesterol in…
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Blasticidin S HCl
G-BiosciencesBlasticidin S is used as a selection agent for transformed cells that contain the resistance genes bls, bsr, or BSD. Also used to study protein synthesis at the level of peptide bond formation. Soluble in water PubChem Chemical ID 16760315 Features CAS#: 3513-03-9 Molecular…
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Rapamycin
G-BiosciencesMode of action and Anti-microbial spectrum Rapamycin, a macrocyclic triene antibiotic, possesses immunosuppressant, anti-proliferative, and anti-cancer activity. Inhibition by rapamycin results in cell cycle arrest in G1. Rapamycin also has been shown to have a role in life span extension in…
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Actinomycin D from Streptomyces parvalus
MP BiomedicalsActinomycin D is a polypeptide antibiotic first described by Waksman. It is bacteriostatic in nature, especially towards gram negative bacteria, and also has anti-tumor activity. Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of…
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Bialaphos
G-BiosciencesMOLECULAR BIOLOGY GRADE Bialaphos is a tripeptide antibiotic that is used in transformation experiments of many species of plants that make use of the bar gene for selection. In corn it is more effective than glufosinate. In wheat, bialaphos was the most reliable selection criteria used to…
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Tobramycin
MP BiomedicalsTobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius and used to treat various types of bacteria infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas. It works by binding to a site on bacterial 30S and 50S ribosome,…
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Amphotericin B from Streptomyces sp.
MP BiomedicalsAmphotericin B is an antimicrobial/antifungal agent effective against yeast and other fungi. It is a mixture of polyenes. It interrupts cell membrane permeability by binding sterols resulting in the loss of low molecular weight compounds from the cell. Amphotericin B may be toxic to some insect…
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Hygromycin B from Streptomyces hygroscopicus
MP BiomedicalsHygromycin B is an antibiotic substance isolated from Streptomyces hygroscopicus. Its mode of action is the inhibition of protein synthesis, by inducing the misreading of the m-RNA template in the prokaryote, (E. coli, at 100 mg/mL), lower eukaryotes (e.g., yeast, at 200 mg/mL) and higher…
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Tobramycin
MP BiomedicalsTobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. It is effective against gram-negative bacteria, especially the Pseudomonas species. Tobramycin has been used: to study the effect of tobramycin on bacteriophage infected biofilms to study…
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Paclitaxel from Taxus brevifolia (Pacific Yew Bark)
MP BiomedicalsPaclitaxel has been used as a component of the dechorionation buffer for Gryllus bimaculatus eggs. Paclitaxel has also been used for studying its effect on the movement of all-trans retinoic acid (ATRA) differentiated NB4 cells. Antitumor and antileukemic agent which lowers the critical…
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Compound 48/80
MP BiomedicalsCompound 48/80 is a oligomeric mixture of condensation products from N-methyl-p-methoxyphenethylamine and formaldehyde. It is a mixture of low-molecular weight polymers having a degree of polymerization between 3 to 6. Protein G activator similar to mastoparan. Calmodulin and platelet PLC…