The Alpillo Plate Cushion compensates for physical tolerances between labware and pipettor that can make automated precision pipetting difficult. Labware variations, misaligned pipet heads, calibration errors, mechanical wear, or tip loading variability are but a few of the problems that often lead to inaccurate positioning between tips and labware. Whether the task is to get the last microliter out of a well, or to touch off small volumes in a dry well, the Alpillo makes these tasks easy by providing flexible plate support.