Synonyms: MGC40331; RIG-B; UBE2L6; UbcH8; Ubiquitin-protein ligase L6; Ubiquitin/ISG15-conjugating enzyme E2 L6
Purity: >=95% (SDS-PAGE)
Storage: -70C
UNSPSC Code: 12352200
General description: Ubiquitin-conjugating enzyme E2 (UBE2E2) is a protein that in humans is encoded by the UBE2E2 gene. Amino acid sequence within the UBC domain of UBE2E2 shares over 90% identity with human UbcH6, mouse UbcM2, and Drosophila UbcD2, whereas the N-terminal region shows little amino acid sequence similarity with known proteins. The UBE2E2 protein forms a thioester bond with ubiquitin in an E1-dependent manner and mediates the transfer of ubiquitin from a ubiquitin-activating enzyme (E1) to a substrate protein or E3 ligase.
Physical form: 75 muL of a 40 muM solution (3 nmoles) in 20 mM Tris, pH 7.4, 150 mM NaCl, 10 mM DTT and 10% glycerol.
Preparation Note: Centrifuge the vial prior to opening.
RIDADR: NONH for all modes of transport
WGK Germany: 3