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MilliporeSigma

Anti-MCF2L (N-terminal) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution

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Synonyms: ARHGEF14; DBS; MCF2L

Storage: -20C

UNSPSC Code: 12352203

Features and Benefits: Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Application: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Biochem/physiol Actions: Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.

Immunogen: Recombinant fragment corresponding to a region within amino acids 84 and 367 of Dbs according to NP_001106203

Physical form: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

RIDADR: NONH for all modes of transport

WGK Germany: 1

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Product Detail
Thomas No.
C890X49
Mfr. No.
SAB2701123-100UL
Description
ANTI-MCF2L (N-TERMINAL) 100UL

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Product C890X49 is restricted and can only be purchased by customers with a web profile linked to a Thomas Business Account - Click here to login or create your web profile. If you do not have a Thomas Business Account, please Contact Us and someone will respond with details on how to apply for a business account with us.

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