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Corning® BioCoat™ Collagen IV-coated Culture Dishes

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Type IV Collagen is a ubiquitous component in basement membranes and provides the major structural support for this matrix. When the Collagen IV meshwork is assembled, it provides a scaffold for the assembly of other basement membrane components through interactions with laminin, entactin/nidogen, and heparan sulfate proteoglycan. Collagen IV is useful as a substrate for growth of epithelial, endothelial, muscle, and nerve cells. Collagen plays a role in the regulation of cell growth, differentiation and adhesion, as well as tissue formation. 

Applications include:       

  • Promotion of cell attachment and spreading   
  • Cell differentiation and neurite outgrowth     
  • Increased proliferation of PC12 cells     
  • Studies of effects of collagen IV on cell behavior     
  • Cell adhesion assays  

Source: Engelbreth-Holm-Swarm (EHS) lathrytic mouse tumor  

Quality Control   

  • Tested for ability to initiate differentiation (neurite outgrowth) of NG-108 rat glioma/mouse neuroblastoma cells   
  • Tested and found negative for bacteria and fungi     

Collagen IV purity >90% by SDS-PAGE  

Storage:  2°C to 8°C. Do not freeze.

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Thomas No.
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Corning® BioCoat™ Collagen IV 100 mm TC-treated Culture Dishes, 5/Pack, 10/Case
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Thomas No.
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Corning® BioCoat™ Collagen IV 60 mm TC-treated Culture Dishes, 5/Pack, 20/Case
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