The Millipak are 0.22 µm membrane filters designed as a safe and efficient barrier against particulates and bacteria.
The Millipak devices use the unique, clean stacked disc design that eliminates the risks of particulate-producing woven downstream support found in many pleated membrane capsules.
The Millipak stacked disc concept offers several benefits
- Adequate support of the flat 0.22 µm membrane, which is supported by a rigid plastic disc with channels to ensure at the same time a high water flow and a resistance to pressure variations without risk of membrane rupture
- Membrane heat sealing on the support that eliminates risks of contamination that may occur when the membrane is bound by solvent
- High surface in a small volume, with a minimum "dead volume"
The Millipak filters were originally designed for sterilizing filtration of pharmaceutical products and culture media.
The 0.22 µm filtration membranes used in the Millipak have been validated for bacteria removal following the HIMA rules, using a challenge with Pseudomonas Diminuta at 107 organisms / cm² of membrane. The bacteria retention efficiency has been correlated during validation studies with the non destructive bubble point and air diffusion tests in order to allow the verification of bacteria retention for each device at the end of the manufacturing process.