Technology

The core technology of Greiner Bio-One’s Magnetic 3D Cell Culture is the magnetization of cells with biocompatible NanoShuttle™-PL. The reproducible formation of one spheroid per well in an F-bottom plate with Cell-Repellent surface is forced by magnets either by levitation or bioprinting, to form structurally and biologically representative 3D models in-vitro

Advantages of the magnetic 3D cell culture (m3D) technology are:

• 3D in a 2D workflow
• Reproducible spheroid formation
• Scalable – 6 Well to 1536 Well
• Performed on a flat surface optimal for high-resolution microscopy and HTS
• Rapid 3D culture formation within 24 hours for most cell types
• No specialized equipment or media
• Easy media changes and co-culture of different cell types
• Compatible with fluorescence microscopy, Western blotting, qRT-PCR, Flow Cytometry, viability assays, chemiluminescence, etc.
• Ready for automation
• Biocompatible nanoparticles to magnetize cells

Products:

• Bioprinting Kits
• BiO Assay™ Kits
• Spheroid and Holding Drives
• Bio-Assembler™ Kits
• Levitating Drive, Concentrating Drive
• n3Dock Imaging Kit