RESOLVOSIL BSA-7
Silica-based protein phase for HPLC enantiomer separation
Features
- Base material NUCLEOSIL® silica, particle size 7 µm, pore size 300 Å
- Chiral selector bovine serum albumin (BSA) · USP L75
- Separation based on selective interaction of proteins with low molecular compounds, i. e. principles of bioaffinity, including hydrophobic interactions (similar to a true reversed phase), interactions of polar groups and steric effects
Eluent in column 0.1 M phosphate buffer pH 7.5, 2 % 1-propanol
Recommended application: amino acid derivatives, aromatic amino acids, aromatic sulphoxides, barbiturates, benzodiazepinones, benzoin and benzoin derivatives, β-blockers, coumarin derivatives, and for monitoring stereoselective microbial and enzymatic conversions