NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:
- Totally spherical particle shape
- Outstanding surface microstructure
- High pressure stability
- Low metal content
NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® C18 ec, analytical HPLC columns
Medium density octadecyl (ODS) modification with exhaustive endcapping, USP L1
Key features:
- Ideal and reliable standard RP phase (110 Å) for daily routine analysis and up-scaling for preparative HPLC
Technical characteristics:
- Pore size 110 Å with particle sizes 3 μm and 5 μm; 7 μm, 10 μm, 12 μm, 16 μm, 20 μm, 30 μm and 50 μm for preparative separations
- pH stability 1–9; high reproducibility from lot to lot
- Carbon content 17.5 %
Recommended application:
- Basic, neutral or acidic drugs; derivatized amino acids; pesticides; fat-soluble vitamins; aldehydes and ketones; phenolic compounds