NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:
- Totally spherical particle shape
- Outstanding surface microstructure
- High pressure stability
- Low metal content
NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® C18 HTec
Nonpolar high density monomeric octadecyl modification with high capacity, USP L1
Key features:
- Reliable and durable standard RP phase for up-scaling to preparative scale, suited for LC/MS
- High loadability and excellent stability
- Outstanding base deactivation
Technical characteristics:
- High density octadecyl (ODS, BDS) modification
- Pore size 110 Å
- Particle sizes 1.8 µm (UHPLC), 3 µm, 5 μm, 7 μm and 10 μm for analytical and preparative separations
- pH stability 1–11
- Carbon content 18 %
Recommended application: Sophisticated analytical and preparative separations of basic, neutral and acidic pharmaceuticals, derivatised amino acids, pesticides, fat-soluble vitamins, aldehydes, ketones and phenolic compounds