LiChrospher® RP-18 is a reliable and versatile traditionally produced spherical silica gel carrier with C-18 reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds. This sorbent is packed into a LiChroCART® 250-4 HPLC cartridge. The connection to the HPLC system is being accomplished by use of the manu-CART® NT cartrige holder (1.51486).