H-CX (hydrophobic/cation) is a mixed-mode sorbent optimized for basic drug extraction from biological fluids. The dual retention mechanism allows an extensive interference elution regime, removing salts, polar interferences, peptides, and proteins prior to analyte elution. H-CX is a commonly use sorbent for many drugs of abuse applications. Columns are made of polypropylene and feature Luer-slip outlet.