Corning Spin-X UF centrifugal concentrators offer a simple, one step procedure for concentrating or desalting proteins and other biomolecules with 90% or better recovery.
- Integrated dead stop design eliminates risk of spinning to dryness; no respinning necessary
- Low binding polyethersulfone (PES) membranes are available with five molecular weight cut-offs (MWCO): 5,000, 10,000, 30,000, 50,000 and 100,000 to meet all of your concentrating needs. Choose a MWCO 1/2 to 1/3 smaller than the protein to be concentrated
- The MWCO and graduations are printed right on the side of the concentrator tube to avoid mix-ups
Spin-X UF 500 concentrators require fixed angle rotors. Minimum rotor angle is 40º. Spin-X UF 500 concentrators are for samples up to 500 µL. The patented vertical membrane design and thin channel filtration chamber (U.S. Patent No. 5,647,990), minimizes membrane fouling and provides fast, high-speed concentrating, even with particle laden solutions.
Spin-X UF 6 concentrators can be used with either swinging bucket or fixed angle rotors; minimum rotor angle is 25º. Spin-X UF 6 concentrators are for samples up to 6 mL.
Spin-X UF 20 concentrators can be used with either swinging bucket or fixed angle rotors; minimum rotor angle is 25º. Spin-X UF 20 concentrators are for samples up to 20 mL, 14 mL if using fixed angle rotors.
Corning Spin-X UF Applications
- Concentration, desalting of proteins, enzymes, monoclonal antibodies, immunoglobulins
- Removal of labeled amino acids and nucleotides
- HPLC sample preparation
- De-proteinization of samples
- Recovery of biomolecules from cell culture supernatants, lysates
- Concentrating virus from cell culture supernatants