These convenient, ready-to-use tissue culture flasks are coated with extra-cellular matrix proteins (ECM) or synthetic peptides. Coating provides an inert scaffolding that helps regulate cell growth and proliferation. It simulates the cells' natural environment, which facilitates adherence, differentiation, proliferation, and longevity in many cell types. Flasks also feature a canted neck, plug seal, "Best Before" date, and a lot number on each pack. Flasks are nonpyrogenic and DNase- and RNase-free. All 650mL flasks feature a high profile design.