Wound closure is the most important principle for the management of skin loss injuries; this clinical achievement is possible with the use of porcine xenograft, which mimics the patient's own skin. The proven clinical success of porcine xenograft is built on over 40 years of experience in burn wound management. Immediately soothing upon application, porcine tissue provides an environment that protects the migration and proliferation of epithelial cells and minimizes painful dressing changes. Once adherent, patient activities may be resumed while the natural healing process continues undisturbed. Anatomically close to human skin, porcine xenograft provides superior product consistency at significantly less cost than allograft and is readily available. The CPT code range of 15271-15278 fully supports the use of porcine xenograft for the management of burns.